Recombinant Human BST2 Protein，His

BST2, also known as tetherin or CD317, is a type II transmembrane protein that plays a critical role in the innate immune response against viral infections. It was first identified as an interferon-inducible gene and has since been recognized for its ability to inhibit the release of newly formed virions from infected cells, effectively trapping them on the cell surface. This property is particularly important in the context of HIV-1 and other enveloped viruses, as BST2 can restrict their propagation. The protein exerts its effects through its unique mechanism of tethering viral particles to the cell membrane, thereby preventing their budding and subsequent spread. However, many viruses have evolved mechanisms to counteract BST2, demonstrating the ongoing arms race between viral pathogens and the host immune system. Research into BST2 has been expanding rapidly, exploring its potential as a therapeutic target for enhancing antiviral responses and understanding its regulatory role in various physiological and pathological processes, including cancer progression and immune regulation. The study of BST2 has also uncovered its broader implications in cell signaling and interactions with other cellular proteins. Hence, the characterization and functional analysis of BST2 reconcile its significance not only in virology but also in immunology and therapeutic development.