Analytical Data
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Gene name
MUC13
- Application
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Alternative Names
MUC13；DRCC1；RECC；Mucin-13
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H3R2
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Expression Region
19-421aa
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AA Sequence
TNQGNSADAVTTTETATSGPTVAAADTTETNFPETASTTANTPSFPTATSPAPPIISTHSSSTIPTPAPPIISTHSSSTIPIPTAADSESTTNVNSLATSDIITASSPNDGLITMVPSETQSNNEMSPTTEDNQSSGPPTGTALLETSTLNSTGPSNPCQDDPCADNSLCVKLHNTSFCLCLEGYYYNSSTCKKGKVFPGKISVTVSETFDPEEKHSMAYQDLHSEITSLFKDVFGTSVYGQTVILTVSTSLSPRSEMRADDKFVNVTIVTILAETTSDNEKTVTEKINKAIRSSSSNFLNYDLTLRCDYYGCNQTADDCLNGLACDCKSDLQRPNPQSPFCVASSLKCPDACNAQHKQCLIKKSGGAPECACVPGYQEDANGNCQKCAFGYSGLDCKDKFQL
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Molecular Weight
44.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MUC13 is a member of the mucin family of glycoproteins, which are heavily glycosylated proteins playing crucial roles in cellular processes such as signaling, adhesion, and protection. It is primarily expressed in epithelial tissues and has been found to be upregulated in various cancers, including pancreatic, gastric, and colorectal cancers. This aberrant expression suggests that MUC13 may contribute to tumorigenesis, and it has garnered attention as a potential biomarker for cancer diagnosis and a target for therapeutic intervention. Recent studies have indicated that MUC13 is involved in important cellular pathways, including inflammation, cell proliferation, and the epithelial-to-mesenchymal transition (EMT), which is critical for cancer metastasis. To further explore the functional roles and mechanisms of MUC13 in cancer biology, researchers have focused on the production and characterization of recombinant MUC13 protein. This recombinant protein serves as a valuable tool for studying its structure, glycosylation patterns, and interactions with other cellular molecules. Understanding these aspects of MUC13 could lead to deeper insights into its role in cancer progression and may aid in the development of targeted therapies. Additionally, the recombinant MUC13 protein can be utilized in various experimental settings, including cell-based assays and antibody generation, to facilitate research aimed at uncovering its biological significance and potential clinical applications. Overall, the study of MUC13 and its recombinant forms presents a promising avenue for advancing cancer research and improving therapeutic strategies.
