Analytical Data
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Gene name
MUC12
- Application
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Alternative Names
MUC12；MUC11；Mucin-12
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKN1
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MUC12, a member of the mucin family of glycoproteins, plays a crucial role in various biological processes, including cellular signaling, immune response, and the maintenance of epithelial integrity. Research on MUC12 has gained traction due to its potential implications in cancer biology, particularly in tumor progression and metastasis, as abnormal expression of mucins is frequently associated with malignant transformations. The interest in MUC12 is fueled by its distinct structural features, including tandem repeats rich in serine and threonine, which are vital for its function and interaction with ligands. Additionally, MUC12 has been implicated in the modulation of the tumor microenvironment, influencing cell adhesion and migration. Consequently, the production and study of recombinant MUC12 protein can facilitate a deeper understanding of its biological roles, help elucidate its mechanisms in cancer development, and potentially assist in the identification of novel therapeutic targets. Current investigations involve the characterization of the protein's biochemical properties, its expression patterns in various cancer types, and exploration of its utility as a biomarker for diagnosis and prognosis. Overall, the research on recombinant MUC12 protein holds promise for advancing our knowledge in cancer biology and enhancing therapeutic strategies.
