Analytical Data
-
Gene name
FOXD4
- Application
-
Alternative Names
FKHL9 ; Forkhead box D4; Forkhead box protein D4; Forkhead Drosophila homolog like 9; Forkhead like 9; Forkhead related activator 5; Forkhead related protein FKHL9; Forkhead related transcription factor 5; Forkhead-related protein FKHL9; Forkhead-related transcription factor 5; FOXD4; FOXD4_HUMAN; FOXD4A
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q12950
-
Expression Region
1-439aa
-
AA Sequence
MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS
-
Molecular Weight
73.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXG1B is a member of the forkhead box (FOX) family of transcription factors, which play critical roles in various biological processes, including development, differentiation, and cellular metabolism. Research into FOXG1B has gained prominence due to its significant implications in neurodevelopmental disorders, particularly in relation to brain formation and function. Mutations or dysregulation of FOXG1B have been associated with conditions such as intellectual disability and epilepsy, underscoring its importance in neuronal development. The study of recombinant FOXG1B protein has been initiated to elucidate its structure-function relationships, regulatory mechanisms, and interactions with other proteins involved in neuronal development. Understanding the functional properties of FOXG1B is crucial for developing potential therapeutic strategies targeting disorders linked to its dysfunction. Current research efforts aim to produce and characterize the recombinant form of FOXG1B, using techniques such as molecular cloning and protein expression systems. This will enable scientists to investigate the protein's binding affinities, target genes, and the pathways it influences during neurogenesis. By unveiling the molecular details of FOXG1B's action, researchers hope to provide insights that may pave the way for innovative interventions in neurodevelopmental disorders associated with FOXG1B anomalies.
