Analytical Data
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Gene name
FOXD4L4
- Application
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Alternative Names
FOXD4L4; FOXD4B; FOXD4L2Forkhead box protein D4-like 4; FOXD4-like 4; Forkhead box protein D4-like 2; Forkhead box protein D4B; Myeloid factor-gamma
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WXT5
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Expression Region
1-416aa
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AA Sequence
MNLPRAERPR STPQRSLRDS DGEDGKIDVL GEEEDEDEVE DEEEEARQQF LEQSLQPGLQ VARWGGVALP REHIEGGGGP SDPSEFGTKF RAPPRSAAAS EDARQPAKPP YSYIALITMA ILQNPHKRLT LSGICAFISG RFPYYRRKFP AWQNSIRHNL SLNDCFVKIP REPGHPGKGN YWSLDPASQD MFDNGSFLRR RKRFKRHQLT PGAHLPHPFP LPAAHAALHN PHPGPLLGAP APPQPVPGAY PNTAPGRRPY ALLHPHPLRY LLLSARVYAG APKKAEGADL ATPAPFPCCS PHLVLSLGRR ARVWRRHREA DASLSALRVL CKGSGERVQG LRRVCPRPRG ATATCSSDHQ ACCIPKPLPL CCKCPPPLLL GQFCSNSSSI RRTAPTAALP PRARCWAGTC RPRRRC
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Molecular Weight
45.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOXD4L4 (Forkhead Box D4-Like 4) is a member of the forkhead box (FOX) transcription factor family, which plays crucial roles in regulating developmental processes, cellular differentiation, and metabolic pathways. Understanding the biological functions of FOXD4L4 is of significant interest due to its potential implications in various diseases, including cancer and neurodevelopmental disorders. The protein's structure features a highly conserved forkhead domain, which is essential for DNA binding and transcriptional regulation. Recent studies have highlighted FOXD4L4 as a critical player in cellular processes such as signal transduction, stem cell maintenance, and tissue regeneration. Research has shown that dysregulation of FOXD4L4 expression is associated with abnormal cell proliferation and differentiation, emphasizing its role in maintaining cellular homeostasis. As a result, elucidating the signaling pathways and molecular mechanisms involving FOXD4L4 could provide valuable insights into its functions in health and disease. Furthermore, recombinant FOXD4L4 protein is being explored as a tool for functional assays, facilitating the study of its interactions with target genes and other regulatory proteins. Overall, exploring FOXD4L4 through recombinant protein studies holds promise for advancing our understanding of its biological functions and therapeutic potential.
