Analytical Data
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基因名
HIST2H2AA3
- Application
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别名
HIST2H2AA3；H2AFO；HIST2H2AA；HIST2H2AA3；Histone H2A type 2-A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04908
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表达区间
2-130aa
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氨基酸序列
SGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY SERVGAGAPV YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR VTIAQGGVLP NIQAVLLPKK TESHHKAKGK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIST2H2AA3 is a member of the histone H2A family, which plays a critical role in the structural integrity and regulation of chromatin within eukaryotic cells. As a core component of the nucleosome, HIST2H2AA3 is involved in the packaging of DNA, thereby influencing gene expression, DNA repair, and replication processes. Research into HIST2H2AA3 has gained momentum due to its potential implications in various biological processes and diseases, including cancer and developmental disorders. The recombination and expression of the HIST2H2AA3 protein provide valuable insights into the functional dynamics of histone variants and their post-translational modifications. Investigating the structure and function of this recombinant protein is essential for understanding chromatin remodeling mechanisms, as histone variants can exhibit distinct roles compared to conventional histones. Moreover, recombinant HIST2H2AA3 can serve as a useful tool in epigenetic studies, allowing researchers to explore the effects of specific histone modifications on gene expression and cellular function. Overall, the study of HIST2H2AA3 recombinant protein is pivotal for elucidating the complexities of gene regulation at the chromatin level, potentially leading to novel therapeutic strategies for related diseases.
