Analytical Data
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基因名
HIST1H2AJ
- Application
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别名
HIST1H2AJ；H2AFE；HIST1H2AJ；Histone H2A type 1-J
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99878
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表达区间
2-128aa
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氨基酸序列
SGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHHKTK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIST1H2AJ is a member of the histone H2A family, involved in the structural organization of chromatin and regulation of gene expression. Histone proteins play a crucial role in packaging DNA into nucleosomes, allowing for efficient storage within the nucleus and influencing DNA accessibility for transcription, replication, and repair. Mutations and dysregulation of histone variants like HIST1H2AJ have been associated with various diseases, including cancer, making them significant targets for biological research. The recombinant production of HIST1H2AJ provides opportunities to study its structural properties, interactions with DNA, and functional roles in chromatin dynamics. By characterizing this histone variant, researchers aim to better understand its contributions to epigenetic regulation and cellular processes, which could lead to novel therapeutic strategies for diseases linked to histone modifications. Moreover, the study of HIST1H2AJ sheds light on the evolutionary conservation of histone variants and their implications in organismal development and differentiation. Overall, the exploration of HIST1H2AJ at a molecular level enhances our comprehension of chromatin biology and its impact on gene regulation.
