Cat: PA1000-8635

Recombinant Human MPP2 Protein,His

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Analytical Data

  • Gene name

    MPP2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    MPP2;DLG2;MAGUK p55 subfamily member 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q14168

  • Expression Region

    1-576aa

  • AA Sequence

    MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK VIMVLWFMQQ NVFVPMKYML KYFGAHERLE ETKLEAVRDN NLELVQEILR DLAHVAEQSS TAAELAHILQ EPHFQSLLET HDSVASKTYE TPPPSPGLDP TFSNQPVPPD AVRMVGIRKT AGEHLGVTFR VEGGELVIAR ILHGGMVAQQ GLLHVGDIIK EVNGQPVGSD PRALQELLRN ASGSVILKIL PSYQEPHLPR QVFVKCHFDY DPARDSLIPC KEAGLRFNAG DLLQIVNQDD ANWWQACHVE GGSAGLIPSQ LLEEKRKAFV KRDLELTPNS GTLCGSLSGK KKKRMMYLTT KNAEFDRHEL LIYEEVARMP PFRRKTLVLI GAQGVGRRSL KNKLIMWDPD RYGTTVPYTS RRPKDSEREG QGYSFVSRGE MEADVRAGRY LEHGEYEGNL YGTRIDSIRG VVAAGKVCVL DVNPQAVKVL RTAEFVPYVV FIEAPDFETL RAMNRAALES GISTKQLTEA DLRRTVEESS RIQRGYGHYF DLCLVNSNLE RTFRELQTAM EKLRTEPQWV PVSWVY

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The research on MPP2 (Mitochondrial Processing Peptidase subunit 2) recombinant protein has gained significant attention due to its essential role in mitochondrial function and protein maturation. MPP2 is a crucial component of the mitochondrial processing peptidase complex, which is responsible for cleaving pre-proteins imported into mitochondria, allowing them to achieve their functional forms. Understanding MPP2's structure and mechanism can provide insights into mitochondrial biogenesis, dynamics, and overall cellular metabolism. Moreover, as mitochondrial dysfunction is implicated in various diseases, including neurodegenerative disorders and metabolic syndromes, studying MPP2 can unravel potential therapeutic targets. The production of recombinant MPP2 not only enables the exploration of its biochemical properties but also facilitates the development of diagnostic tools and potential treatments. By employing advanced techniques in molecular biology and biochemistry, researchers aim to elucidate the regulatory mechanisms governing MPP2 activity and its role in maintaining mitochondrial integrity. This knowledge could ultimately contribute to innovative strategies for combating mitochondrial-related diseases and enhancing our understanding of cellular energy metabolism.

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