Analytical Data
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Gene name
UBTD1
- Application
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Alternative Names
UBTD1Ubiquitin domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HAC8
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Expression Region
1-227 aa
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AA Sequence
MGNCVGRQRR ERPAAPGHPR KRAGRNEPLK KERLKWKSDY PMTDGQLRSK RDEFWDTAPA FEGRKEIWDA LKAAAYAAEA NDHELAQAIL DGASITLPHG TLCECYDELG NRYQLPIYCL SPPVNLLLEH TEEESLEPPE PPPSVRREFP LKVRLSTGKD VRLSASLPDT VGQLKRQLHA QEGIEPSWQR WFFSGKLLTD RTRLQETKIQ KDFVIQVIIN QPPPPQD
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Molecular Weight
25.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UBTD1, a member of the UBA (ubiquitin-associated) domain-containing proteins, has garnered attention in recent years due to its potential roles in various cellular processes, particularly those related to protein degradation and cellular stress response. This protein is known to interact with ubiquitin-conjugating enzymes and is believed to influence the ubiquitin-proteasome system, which is crucial for maintaining cellular homeostasis by regulating protein turnover. Dysregulation of UBTD1 has been implicated in several diseases, including cancer, where it may contribute to the degradation of tumor suppressor proteins or the stabilization of oncogenic factors. Consequently, recombinant UBTD1 protein has emerged as a research focus to better understand its structure-function relationship, binding interactions, and cellular mechanisms. The production of UBTD1 in a recombinant form allows scientists to conduct detailed biochemical assays and structural studies, paving the way for potential therapeutic interventions targeting its pathways. Understanding UBTD1's role in mediating cellular responses could provide insights into novel strategies for combating diseases associated with protein misfolding or degradation dysregulation. Thus, ongoing research into UBTD1 recombinant protein aims to elucidate its functional significance and therapeutic potential, contributing to the broader field of protein-based drug development and disease management.
