Analytical Data
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Gene name
PLEKHA1
- Application
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Alternative Names
PLEKHA1；TAPP1；Pleckstrin homology domain-containing family A member 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HB21
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Expression Region
1-404aa
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AA Sequence
MPYVDRQNRI CGFLDIEENE NSGKFLRRYF ILDTREDSFV WYMDNPQNLP SGSSRVGAIK LTYISKVSDA TKLRPKAEFC FVMNAGMRKY FLQANDQQDL VEWVNVLNKA IKITVPKQSD SQPNSDNLSR HGECGKKQVS YRTDIVGGVP IITPTQKEEV NECGESIDRN NLKRSQSHLP YFTPKPPQDS AVIKAGYCVK QGAVMKNWKR RYFQLDENTI GYFKSELEKE PLRVIPLKEV HKVQECKQSD IMMRDNLFEI VTTSRTFYVQ ADSPEEMHSW IKAVSGAIVA QRGPGRSASS EHPPGPSESK HAFRPTNAAT ATSHSTASRS NSLVSTFTME KRGFYESLAK VKPGNFKVQT VSPREPASKV TEQALLRPQS KNGPQEKDCD LVDLDDASLP VSDV
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLEKHA1, or Pleckstrin Homology Domain-Containing A1, is a protein that has garnered significant attention in the field of cellular biology due to its involvement in various signaling pathways and cellular processes. Initially identified for its role in lipid binding and cellular signaling, PLEKHA1 has been implicated in the regulation of cell morphology, migration, and proliferation. Research indicates that it serves as a crucial player in the organization of the cytoskeleton and membrane dynamics, which are essential for normal cellular functions. Furthermore, studies have suggested a potential link between PLEKHA1 and several diseases, including cancer, where its expression levels and activity may influence tumor progression and metastasis. The recombinant expression of PLEKHA1 enables researchers to perform detailed functional studies, dissecting its interactions with other cellular components and elucidating its biochemical properties. This has opened up opportunities for therapeutic targeting and biomarker development. Overall, the study of PLEKHA1 and its recombinant forms is pivotal for a deeper understanding of its biological roles and potential implications in health and disease.
