Analytical Data
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Gene name
TNRC6A
- Application
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Alternative Names
TNRC6A；CAGH26；KIAA1460；TNRC6；Trinucleotide repeat-containing gene 6A Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NDV7
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TNRC6A (trinucleotide repeat-containing gene 6A) is a key component of the RNA-induced silencing complex (RISC), playing a crucial role in post-transcriptional gene regulation via microRNA (miRNA) mechanisms. It is primarily involved in the cellular processes of mRNA degradation and translational repression, thereby influencing gene expression and cellular functions. Dysregulation of TNRC6A has been implicated in various diseases, including cancers and neurological disorders, making it a significant target for biomedical research. The recombinant expression of TNRC6A protein allows researchers to investigate its functional roles, protein interactions, and structural characteristics in detail. By producing TNRC6A as a recombinant protein, scientists can study its properties in vitro, assess its interactions with other RISC components, and explore its potential as a therapeutic target. Understanding the molecular mechanisms underlying TNRC6A's functions could provide insights into the pathways it regulates and contribute to the development of novel therapeutic strategies for diseases associated with miRNA dysregulation.
