Analytical Data
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Gene name
TWIST2
- Application
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Alternative Names
bHLHa39; Class A basic helix-loop-helix Protein 39; Dermis expressed Protein 1; Dermis-expressed Protein 1; DERMO 1; Dermo-1; DERMO1; MGC117334; Twist 2; Twist homolog 2 (Drosophila); Twist homolog 2; Twist related bHLH Protein Dermo1; Twist related Protein 2; Twist-related Protein 2; Twist2; TWST2_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WVJ9
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Expression Region
1-160 aa
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AA Sequence
MEEGSSSPVS PVDSLGTSEE ELERQPKRFG RKRRYSKKSS EDGSPTPGKR GKKGSPSAQS FEELQSQRIL ANVRERQRTQ SLNEAFAALR KIIPTLPSDK LSKIQTLKLA ARYIDFLYQV LQSDEMDNKM TSCSYVAHER LSYAFSVWRM EGAWSMSASH
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Molecular Weight
18.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TWIST2 is a member of the Twist family of basic helix-loop-helix (bHLH) transcription factors, which play crucial roles in various biological processes, including cell differentiation, development, and epithelial-mesenchymal transition (EMT). Dysregulation of TWIST2 has been implicated in several pathological conditions, including congenital disorders and various forms of cancer. The study of TWIST2 recombinant proteins has gained significant attention as researchers aim to elucidate its functional mechanisms and potential therapeutic applications. By generating and characterizing recombinant TWIST2 proteins, scientists can investigate its interaction with target genes and regulatory pathways, furthering our understanding of its role in tumorigenesis and developmental biology. Moreover, recombinant TWIST2 proteins provide valuable tools for functional assays, enabling the exploration of its influence on cellular behaviors, such as migration and invasion. Understanding the structure-function relationship of TWIST2 is crucial, as it may reveal novel strategies for targeting TWIST2-related pathways in disease. Overall, research on TWIST2 recombinant proteins holds promise for advancing our knowledge of both fundamental biological processes and the development of innovative therapeutic approaches in regenerative medicine and oncology.
