Analytical Data
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基因名
RI
- Application
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别名
RI;Nuclear receptor-interacting Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12319
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表达区间
26-205aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSVPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of Recombinant Immunoglobulin (RI) proteins has gained significant attention due to their pivotal role in therapeutic applications and in understanding immune responses. RIs are engineered antibodies produced through recombinant DNA technology, allowing for precise modifications in their structure and function. This adaptability enhances their ability to bind specific antigens, making them crucial tools in the development of targeted therapies for various diseases, including cancers, autoimmune disorders, and infectious diseases. The increasing prevalence of conditions that require personalized medicine underscores the importance of RIs, as they can be tailored for improved efficacy and reduced side effects. Additionally, the advancement in biotechnological methods, such as mammalian cell culture and microbial systems, has streamlined the production of these proteins, ensuring high yield and activity. Recent breakthroughs in antibody engineering, including bispecific antibodies and antibody-drug conjugates, highlight the potential of RIs in revolutionizing treatment paradigms. However, challenges remain in ensuring stability, solubility, and immunogenicity of engineered antibodies, driving ongoing research to improve these attributes. The integration of bioinformatics and computational modeling further aids in rational design, facilitating the identification of promising candidates for clinical development. Overall, the research on RI proteins not only enhances our understanding of the immune system but also paves the way for innovative therapeutic strategies, making it a rapidly evolving and impactful field in biotechnology and medicine.












