Analytical Data
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Gene name
ZNF650
- Application
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Alternative Names
DKFZp434P117; DKFZp686N10185; E3 ubiquitin-Protein ligase UBR3; FLJ37422; KIAA2024; MGC126489; N-recognin-3; Ubiquitin-Protein ligase E3-alpha-3; Ubiquitin-Protein ligase E3-alpha-III; Ubr3; UBR3_HUMAN; Zinc finger Protein 650; ZNF 650; ZNF650
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZT12
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Expression Region
1-741 aa
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AA Sequence
MNKRIIEEICRKVTPPVPPKKVTAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTAEPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPISEEEQIYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNPWQRPSNKSIQDLIKEVEELQGRPGAFPSETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGNLCSGGASTAGKRSCLNQLFHVLALHMRLYSIDSEYNPWRKLTQLEEMNPQLGYEEQQPEVPILYHDVTSLLLIQILMMPQPLRKDHFTCIVKVLFTLLYTQALAALSVKCSEEDRSAWKHAGALKKSTCDAEKSYEVLLSFVISELFKGKLYHEEGTQECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLPSCQEEEEFSVLASCLGLLPTFYQTEHPFISASCLDWPVPAFDIITQWCFEIKSFTERHAEQGKALLIQESKWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYKVLEQQWISHTFDHINKRWGPHYNGL
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Molecular Weight
110.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF650 is a member of the zinc finger protein family, which is known for its role in DNA binding and transcription regulation. Recent studies have highlighted the significance of ZNF650 in various cellular processes, including gene expression, cell differentiation, and development. Its unique structure, characterized by multiple zinc finger motifs, enables it to interact with specific DNA sequences, thereby influencing target gene activation or repression. Research into the recombinant expression of ZNF650 has garnered interest due to its potential applications in biotechnology and medicine. Recombinant ZNF650 can serve as a valuable tool for studying gene regulation mechanisms and understanding the molecular pathways involved in diseases. Additionally, exploring its role in developmental biology may provide insights into tissue engineering and regenerative medicine. As ZNF650 is implicated in several pathological conditions, including cancer and neurodegenerative diseases, the production of recombinant ZNF650 could facilitate the development of novel therapeutic strategies. Overall, the investigation of ZNF650, particularly through recombinant technologies, offers a promising avenue for advancing our understanding of gene regulation and its implications in health and disease.
