Analytical Data
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基因名
GLRX3
- Application
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别名
GLRX3；PICOT；TXNL2；Glutaredoxin-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O76003
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表达区间
1-335aa
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氨基酸序列
MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILRGEN
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分子量
64.3kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GLRX3, or Glutaredoxin 3, is a member of the glutaredoxin family, known for its crucial role in redox regulation and cellular responses to oxidative stress. It serves as a thiol-disulfide oxidoreductase, facilitating the reduction of disulfide bonds and contributing to cellular redox homeostasis. Research into GLRX3 has gained momentum due to its implications in various diseases, including cancer and neurodegenerative disorders, where oxidative stress plays a significant role in pathogenesis. The protein's involvement in mitochondrial function and its potential role as a biomarker for oxidative stress-related diseases have further heightened interest in characterizing GLRX3. The recombinant expression of GLRX3 provides a valuable tool for studying its biochemical properties and functional mechanisms. By producing the protein in a controlled environment, researchers can investigate its interactions with other cellular components, elucidate its enzymatic activity, and explore its therapeutic potential. Moreover, understanding the structure-function relationship of GLRX3 can pave the way for the development of novel interventions targeting oxidative stress-related conditions. Overall, GLRX3 is emerging as a significant player in the field of redox biology, and ongoing studies aim to unlock its full potential in clinical applications.
