Analytical Data
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基因名
BMP3
- Application
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别名
BMP3；BMP3A；Bone morphogenetic Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12645
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表达区间
363-472aa
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氨基酸序列
QWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR
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分子量
13.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Bone Morphogenetic Protein 3 (BMP3) is a member of the transforming growth factor-beta (TGF-β) superfamily, which plays a crucial role in bone and cartilage development. Initially discovered for its ability to induce bone formation, BMP3's function has evolved into a deeper understanding of its regulatory roles in various biological processes, including cell differentiation, proliferation, and apoptosis. Research has indicated that BMP3 acts as an antagonist to other BMPs, participating in the complex signaling pathways that govern skeletal homeostasis and development. The recombinant expression of BMP3 has been a focal point in regenerative medicine, as it holds potential for therapeutic applications in bone repair and osteoporosis treatment. Furthermore, studies have revealed that BMP3 is implicated in modulating inflammatory responses and may influence the progression of certain cancers. As a result, the generation and characterization of BMP3 recombinant proteins are pivotal for elucidating its diverse physiological functions and unlocking its therapeutic potential. Understanding the structure-function relationship of BMP3 could lead to innovative solutions for skeletal disorders and other diseases where BMP signaling is dysregulated.
