Analytical Data
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基因名
TTLL7
- Application
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别名
RP5-836J3.2; Testis development Protein NYD-SP30; Ttll7; TTLL7_HUMAN; Tubulin polyglutamylase TTLL7; Tubulin tyrosine ligase like family member 7; Tubulin--tyrosine ligase-like Protein 7
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZT98
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表达区间
1-543 aa
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氨基酸序列
MPSLPQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKRANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKTRGPKGRITHYVVKLFKNT
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分子量
90 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TTLL7, a member of the tubulin tyrosine ligase-like (TTLL) family, has garnered attention in recent years due to its role in post-translational modifications of tubulin, particularly in the addition of tyrosine residues to alpha-tubulin. This modification is critical for regulating microtubule dynamics and stability, influencing various cellular processes, including cell division, intracellular transport, and signaling pathways. Abnormalities in tubulin modifications are linked to several diseases, including cancer and neurodegenerative disorders, making TTLL7 a potential biomarker or therapeutic target. Researchers are investigating the structural and functional properties of TTLL7 to better understand its enzymatic mechanisms and interactions with other proteins. The production of recombinant TTLL7 protein is essential for these studies, allowing for detailed biochemical assays and structural analyses. By elucidating the function of TTLL7, scientists aim to uncover novel aspects of tubulin biology that could pave the way for innovative therapeutic strategies against diseases tied to microtubule dysfunction.
