Analytical Data
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基因名
FBXO16
- Application
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别名
FBXO16; FBX16; F-box only protein 16
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IX29
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表达区间
1-292aa
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氨基酸序列
MMAFAPPKNT DGPKMQTKMS TWTPLNHQLL NDRVFEERRA LLGKWFDKWT DSQRRRILTG LLERCSLSQQ KFCCRKLQEK IPAEALDFTT KLPRVLSLYI FSFLDPRSLC RCAQVCWHWK NLAELDQLWM LKCLRFNWYI NFSPTPFEQG IWKKHYIQMV KELHITKPKT PPKDGFVIAD VQLVTSNSPE EKQSPLSAFR SSSSLRKKNN SGEKALPPWR SSDKHPTDII RFNYLDNRDP METVQQGRRK RNQMTPDFSR QSHDKKNKLQ DRTRLRKAQS MMSRRNPFPL CP
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分子量
34.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FBXO16 is a member of the F-box protein family, which plays a crucial role in the ubiquitin-proteasome system, a key pathway for protein degradation in cells. The function of FBXO16 primarily involves its ability to recognize and bind specific substrates for ubiquitination, thereby regulating various cellular processes such as cell division, differentiation, and response to stress. Recent studies have highlighted the potential implications of FBXO16 in various diseases, including cancer, where its dysregulation may contribute to tumorigenesis and metastasis. Additionally, FBXO16 has been associated with the regulation of circadian rhythms, suggesting its involvement in maintaining cellular homeostasis and adaptation to environmental changes. Understanding the molecular mechanisms by which FBXO16 operates may provide insights into its role in health and disease, paving the way for potential therapeutic interventions targeting its pathway. Given the increasing interest in the development of ubiquitin-based therapies, FBXO16 stands out as a promising candidate for further investigation in the realm of protein homeostasis and disease management.
