Analytical Data
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Gene name
BMP8A
- Application
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Alternative Names
BMP8A；Bone morphogenetic Protein 8A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z5Y6
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Expression Region
264-402aa
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AA Sequence
AVRPLRR RQPKKSNELP QANRLPGIFD DVRGSHGRQV CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLDS CMNATNHAIL QSLVHLMKPN AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BMP8A, or Bone Morphogenetic Protein 8A, is a member of the transforming growth factor-beta (TGF-β) superfamily, which plays a crucial role in various physiological processes such as bone development, regulation of cell growth, and differentiation. Initially identified for its significant role in osteogenesis, BMP8A has garnered attention for its involvement in metabolic pathways, particularly in energy homeostasis and adipogenesis. Research has demonstrated that BMP8A can influence metabolic functions in brown adipose tissue, potentially affecting thermogenesis and energy expenditure. Furthermore, its role in the regulation of insulin sensitivity and its implications in metabolic disorders, such as obesity and diabetes, have led to increased interest in BMP8A as a therapeutic target. The recombinant production of BMP8A protein has become essential for studying its biological functions and mechanisms, enabling researchers to explore its potential applications in regenerative medicine and metabolic disease management. Understanding the structural and functional properties of BMP8A through recombinant technology could provide insights into novel therapeutic strategies, contributing to advances in both tissue engineering and metabolic health. Consequently, BMP8A is not only a key player in developmental biology but also presents opportunities for innovative treatments in metabolic-related diseases.
