Analytical Data
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Gene name
ZNF577
- Application
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Alternative Names
ZNF577; Zinc finger Protein 577
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BSK1
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Expression Region
1-478 aa
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AA Sequence
MSVRREQGSSSGEGSLSFEDVAVGFTREEWQFLDQSQKVLYKEVMLENYINLVSIGYRGTKPDSLFKLEQGEPPGIVEGAAHSQICPGFVIQSRRYAGKDSDAFGGYGRSCLHIKCDKTLTGVKYHRCVKPSSPKSQLNDLQKICAGGKPHECSVCGRAFSRKAQLIQHQRTERGEKPHGCGECGKTFMRKIQLTEHQRTHTGEKPHECSECGKAFSRKSQLMVHQRTHTGEKPYRCSECGKAFSRKCRLNRHQRSHTGEKLYGCSVCGKAFSQKAYLTAHQRLHTGDKPYKCSDCGRTFYFKSDLTRHQRIHTGEKPYECSECEKAFRSKSKLIQHQRTHTGERPYSCRECGKAFAHMSVLIKHEKTHIRETAINSLTVEKPSSRSHTSLYMSELIQEQKTVNTVPIEMPSSGTPPLLNKSERLVGRNVVIVEQPFPRNQAFVVNQEFEQRISLTNEVNVAPSVINYILYLTDIVSE
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Molecular Weight
80.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF577, a member of the zinc finger protein family, plays a crucial role in transcription regulation and various cellular processes. Recent studies have highlighted its involvement in key biological functions, including gene expression regulation, chromatin remodeling, and potential implications in developmental processes and disease mechanisms. Particularly, ZNF577 has been linked to neurodevelopmental disorders and certain cancers, making it a significant target for therapeutic research. The structural characteristics of ZNF577, including its specific zinc finger motifs, are of great interest for understanding its interaction with DNA and other proteins. Additionally, the ability to produce recombinant ZNF577 protein has opened up avenues for detailed functional studies and biochemical assays, enabling researchers to explore its molecular mechanisms more profoundly. By generating and characterizing recombinant ZNF577, researchers aim to elucidate its role within the cellular context, explore its potential as a biomarker, and develop targeted treatments for diseases associated with its dysfunction. This ongoing research holds promise for advancing our knowledge of gene regulation and its implications for human health.
