Analytical Data
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Gene name
TTC5
- Application
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Alternative Names
TTC5Tetratricopeptide repeat Protein 5; TPR repeat Protein 5; Stress-responsive activator of p300; Strap
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N0Z6
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Expression Region
1-440 aa
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AA Sequence
MMADEEEEVK PILQKLQELV DQLYSFRDCY FETHSVEDAG RKQQDVQKEM EKTLQQMEEV VGSVQGKAQV LMLTGKALNV TPDYSPKAEE LLSKAVKLEP ELVEAWNQLG EVYWKKGDVA AAHTCFSGAL THCRNKVSLQ NLSMVLRQLR TDTEDEHSHH VMDSVRQAKL AVQMDVHDGR SWYILGNSYL SLYFSTGQNP KISQQALSAY AQAEKVDRKA SSNPDLHLNR ATLHKYEESY GEALEGFSRA AALDPAWPEP RQREQQLLEF LDRLTSLLES KGKVKTKKLQ SMLGSLRPAH LGPCSDGHYQ SASGQKVTLE LKPLSTLQPG VNSGAVILGK VVFSLTTEEK VPFTFGLVDS DGPCYAVMVY NIVQSWGVLI GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV ATVASRPQCE
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Molecular Weight
48.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TTC5, or Tetratricopeptide Repeat Protein 5, is a protein that has garnered significant interest in the scientific community due to its potential roles in cellular processes and disease mechanisms. Originally identified as a protein that interacts with various partners, TTC5 is known to feature a series of tetratricopeptide repeats, which are motifs commonly associated with protein-protein interactions. Research has indicated that TTC5 may be involved in regulating key biological functions such as cell differentiation, apoptosis, and transcriptional control. Its association with critical pathways, including those related to cancer and neurodegenerative diseases, points to its potential as a therapeutic target. Studies have suggested that alterations in TTC5 expression or function could contribute to disease progression, emphasizing the importance of understanding its molecular mechanisms. Furthermore, the development of recombinant TTC5 proteins has paved the way for in-depth functional studies and potential applications in biomarker discovery and drug development. Overall, the research surrounding TTC5 is crucial for elucidating its role in health and disease, as well as for exploring novel therapeutic strategies.
