Analytical Data
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Gene name
TTC6
- Application
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Alternative Names
TTC6; C14orf25; NCRNA00291Tetratricopeptide repeat Protein 6; TPR repeat Protein 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86TZ1
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Expression Region
1-520 aa
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AA Sequence
MMKYYDLAKF TIYQIAEMDK GLSELSPMQQ ALIYSFCENH DKAIEVLDGI SWNRAEMTMC ALLAKVQMKA KRTKEAVEVL KKALDAISHS DKGPDATAIS ADCLYNLGLC YMEEGNLQMT YKLAITDLTT AISMDKNSYT AFYNRALCYT KIRELQMALT DYGIVLLLDA TETVKLNTFL NRGLIYVELG QYGFALEDFK QAALISRTNG SLCHATAMCH HRINEFEEAV NFFTWALKIN PCFLDAYVGR GNSYMEYGHD EATKQAQKDF LKALHINPAY IKARISFGYN LQAQGKFQKA WNHFTIAIDT DPKNYLAYEG RAVVCLQMGN NFAAMQDINA AMKISTTAEF LTNRGVIHEF MGHKQNAMKD YQDAITLNPK YSLAYFNAGN IYFHHRQFSQ ASDYFSKALK FDPENEYVLM NRAITNTILK KYEEAKEDFA NVIESCPFWA AVYFNRAHFY YCLKQYELAE EDLNKALSLK PNDALVYNFR AKVRGKIGLI EEAMADYNQA LDLEDYASVI
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Molecular Weight
59.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TTC7B (Tetratricopeptide repeat protein 7B) is a protein of growing interest in biomedical research, primarily due to its implications in various cellular processes and human diseases. It plays a crucial role in regulating protein degradation pathways, particularly those involving the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis. Mutations in TTC7B have been linked to a range of disorders, including immunodeficiencies and certain neurodevelopmental disorders, emphasizing its importance in human health. The protein is characterized by its tetratricopeptide repeat motifs, which facilitate protein-protein interactions, suggesting its involvement in complex regulatory networks within cells. Given its pivotal role, researchers are focused on understanding the structure-function relationships of TTC7B, its interactions with other cellular proteins, and its potential as a therapeutic target. Recombining TTC7B in laboratory settings allows for detailed functional studies and the exploration of its biological roles, potentially leading to new interventions for diseases associated with its dysfunction. As research progresses, insights into TTC7B may pave the way for innovative treatments, underlining the protein's significance in molecular biology and medicine.
