Analytical Data
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基因名
TTC30B
- Application
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别名
TTC30B; Tetratricopeptide repeat Protein 30B; TPR repeat Protein 30B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N4P2
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表达区间
1-665 aa
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氨基酸序列
MAGLSGAQIP DGEFTAVVYR LIRNARYAEA VQLLGGELQR SPRSRAGLSL LGYCYYRLQE FALAAECYEQ LGQLHPELEQ YRLYQAQALY KACLYAEATR VAFLLLDNPA YHSRVLRLQA AIKYSEGDLP GSRSLVEQLP SREGGEESGG ENETDGQINL GCLLYKEGQY EAACSKFFAA LQASGYQPDL SYNLALAYYS SRQYASALKH IAEIIERGIR QHPELGVGMT TEGIDVRSVG NTLVLHQTAL VEAFNLKAAI EYQLRNYEAA QEALTDMPPR AEEELDPVTL HNQALMNMDA RPTEGFEKLQ FLLQQNPFPP ETFGNLLLLY CKYEYFDLAA DVLAENAHLI YKFLTPYLYD FLDAVITCQT APEEAFIKLD GLAGMLTEVL RKLTIQVQEA RHNRDDEAIK KAVNEYDETM EKYIPVLMAQ AKIYWNLENY PMVEKIFRKS VEFCNDHDVW KLNVAHVLFM QENKYKEAIG FYEPIVKKHY DNILNVSAIV LANLCVSYIM TSQNEEAEEL MRKIEKEEEQ LSYDDPDKKM YHLCIVNLVI GTLYCAKGNY DFGISRVIKS LEPYNKKLGT DTWYYAKRCF LSLLENMSKH TIMLRDSVIQ ECVQFLEHCE LHGRNIPAVI EQPLEEERMH VGKNTVTYES RQLKALIYEI IGWNI
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分子量
76.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The TTC30B protein, an emerging focus in molecular biology, plays a crucial role in various cellular processes, including cell signaling, cytoskeletal organization, and protein degradation. TTC30B belongs to the tetratricopeptide repeat (TPR) family, known for their involvement in mediating protein-protein interactions. Research has highlighted the significance of TTC30B in the context of neurodevelopmental disorders and cancer, where its dysregulation is often implicated. Its unique structure allows for specific binding to various partner proteins, suggesting that TTC30B may serve as a key modulator in multiple signaling pathways. Furthermore, studies have demonstrated that TTC30B can influence the stability and localization of proteins within the cell, thereby impacting cellular dynamics and responses to external stimuli. Continued investigation into the functional mechanisms of TTC30B not only enhances our understanding of its biological roles but also presents potential therapeutic avenues for diseases characterized by its abnormal expression or function. Understanding the intricacies of TTC30B's interactions and pathways could lead to novel strategies for intervention in conditions linked to its dysregulation, making it a promising candidate for future research in both fundamental biology and translational medicine.
