Analytical Data
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Gene name
PEX2
- Application
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Alternative Names
PEX2;PAF1;PMP3;PMP35;Peroxisome biogenesis factor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P28328
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Expression Region
1-305aa
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AA Sequence
MASRKENAKSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKACLWVFLWRFTIYSKNATVGQSVLNIKYKNDFSPNLRYQPPSKNQKIWYAVCTIGGRWLEERCYDLFRNHHLASFGKVKQCVNFVIGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNICEVGFEYMNRELLWHGFAEFLIFLLPLINVQKLKAKLSSWCIPLTGAPNSDNTLATSGKECALCGEWPTMPHTIGCEHIFCYFCAKSSFLFDVYFTCPKCGTEVHSLQPLKSGIEMSEVNAL
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PEX2, a crucial gene within the peroxisome biogenesis pathway, encodes a protein that plays a vital role in the formation and maintenance of peroxisomes, which are cellular organelles involved in lipid metabolism and the detoxification of reactive oxygen species. Defects in PEX2 are linked to a group of inherited disorders known as peroxisome biogenesis disorders (PBDs), which can lead to severe neurological and metabolic issues. Given the essential functions of peroxisomes, research on PEX2 recombinant protein has gained significance in understanding the molecular mechanisms underlying these disorders. By studying the expression, folding, and functional characteristics of PEX2 protein, researchers aim to elucidate its role in peroxisome assembly and identify potential therapeutic targets for PBDs. Advances in recombinant DNA technology and protein expression systems have enabled the production and detailed analysis of PEX2 protein, paving the way for insights into its interaction with other peroxins and its impact on cellular homeostasis. This line of research is not only pivotal for uncovering the pathogenesis of PBDs but also contributes to the broader fields of cell biology and metabolic research, offering potential strategies for intervention in related diseases.











