Analytical Data
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Gene name
ZNF571
- Application
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Alternative Names
ZNF571; HSPC059; Zinc finger Protein 571
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z3V5
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Expression Region
1-609 aa
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AA Sequence
MPHLLVTFRDVAIDFSQEEWECLDPAQRDLYRDVMLENYSNLISLDLESSCVTKKLSPEKEIYEMESLQWENMGKRINHHLQYNGLGDNMECKGNLEGQEANQEGLYMCVKITCEEKATESHSTSSTFHRIIPTKEKLYKCKECRQGFSYLSCLIQHEENHNIEKCSEVKKHRNTFSKKPSYIQHQRIHTGEKPYECMECGKAFGRTSDLIQHQKIHTNEKPYQCNACGKAFIRGSQLTEHQRVHTGEKPYECKKCGKAFSYCSQYTLHQRIHSGEKPYECKDCGKAFILGSQLTYHQRIHSGEKPYECKECGKAFILGSHLTYHQRVHTGEKPYICKECGKAFLCASQLNEHQRIHTGEKPYECKECGKTFFRGSQLTYHLRVHSGERPYKCKECGKAFISNSNLIQHQRIHTGEKPYKCKECGKAFICGKQLSEHQRIHTGEKPFECKECGKAFIRVAYLTQHEKIHGEKHYECKECGKTFVRATQLTYHQRIHTGEKPYKCKECDKAFIYGSQLSEHQRIHRGEKPYECKQCGKAFIRGSHLTEHLRTHTGEKPYECKECGRAFSRGSELTLHQRIHTGEKPYTCVQCGKDFRCPSQLTQHTRLHN
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Molecular Weight
97.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF571, a member of the zinc finger protein family, has garnered significant interest in recent years due to its potential role in transcriptional regulation and epigenetic modulation. This protein is localized in the nucleus and is thought to participate in various biological processes, including cell differentiation and developmental regulation. Research has indicated that ZNF571 may play a critical role in silencing retrotransposons, thereby protecting genomic stability, which is crucial for normal cellular function and organismal development. Furthermore, abnormalities in ZNF571 expression have been associated with several diseases, including certain cancers, highlighting its potential as a biomarker and therapeutic target. The production of recombinant ZNF571 protein is essential for studying its structure, function, and interactions with other cellular molecules, enabling researchers to elucidate its role in gene regulation. Advances in recombinant DNA technology have made it feasible to produce ZNF571 in sufficient quantities for in vitro studies, paving the way for detailed biochemical and biophysical analyses. Understanding the functional mechanisms of ZNF571 could provide valuable insights into its therapeutic applications and its role in disease mechanisms, underscoring the importance of ongoing research in this area.
