Analytical Data
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基因名
TTC30A
- Application
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别名
TTC30ATetratricopeptide repeat Protein 30A; TPR repeat Protein 30A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86WT1
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表达区间
1-665 aa
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氨基酸序列
MAGLSGAQIP DGEFTALVYR LIRDARYAEA VQLLGRELQR SPRSRAGLSL LGYCYYRLQE FALAAECYEQ LGQLHPELEQ YRLYQAQALY KACLYPEATR VAFLLLDNPA YHSRVLRLQA AIKYSEGDLP GSRSLVEQLL SGEGGEESGG DNETDGQVNL GCLLYKEGQY EAACSKFSAT LQASGYQPDL SYNLALAYYS SRQYASALKH IAEIIERGIR QHPELGVGMT TEGFDVRSVG NTLVLHQTAL VEAFNLKAAI EYQLRNYEVA QETLTDMPPR AEEELDPVTL HNQALMNMDA RPTEGFEKLQ FLLQQNPFPP ETFGNLLLLY CKYEYFDLAA DVLAENAHLT YKFLTPYLYD FLDALITCQT APEEAFIKLD GLAGMLTEQL RRLTKQVQEA RHNRDDEAIK KAVNEYDETM EKYIPVLMAQ AKIYWNLENY PMVEKVFRKS VEFCNDHDVW KLNVAHVLFM QENKYKEAIG FYEPIVKKHY DNILNVSAIV LANLCVSYIM TSQNEEAEEL MRKIEKEEEQ LSYDDPNRKM YHLCIVNLVI GTLYCAKGNY EFGISRVIKS LEPYNKKLGT DTWYYAKRCF LSLLENMSKH MIVIHDSVIQ ECVQFLGHCE LYGTNIPAVI EQPLEEERMH VGKNTVTDES RQLKALIYEI IGWNK
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分子量
76.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TTC30A, a member of the Tetratricopeptide Repeat (TPR) motif-containing protein family, has garnered significant interest in recent years due to its potential roles in cellular processes and disease mechanisms. The TPR motifs are characterized by their ability to mediate protein-protein interactions, which are crucial for various biological functions, including signal transduction, protein folding, and cellular stress responses. Research has indicated that TTC30A may be involved in the regulation of cilia function and the Hedgehog signaling pathway, both vital for proper embryonic development and tissue homeostasis. Dysregulation of these pathways has been linked to several disorders, including cancer and ciliopathies. Preliminary studies have also suggested that TTC30A may influence tumor progression and metastasis, highlighting its potential as a therapeutic target. Understanding the structure-function relationship of TTC30A, as well as its interaction partners, could provide insights into its biological roles and implications in health and disease. Thus, ongoing investigations aim to elucidate the biochemical properties of TTC30A and its involvement in cellular signaling networks, paving the way for novel interventions in related pathologies.
