Analytical Data
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基因名
TRUB2
- Application
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别名
CLONE24922; OTTHUMP00000022257; Probable tRNA pseudouridine synthase 2; RP11 339B21.1; TRUB 2; TruB pseudouridine (psi) synthase homolog 2; TruB pseudouridine (psi) synthase homolog2 (E. coli); trub2; TRUB2_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95900
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表达区间
1-331 aa
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氨基酸序列
MGSAGLSRLH GLFAVYKPPG LKWKHLRDTV ELQLLKGLNA RKPPAPKQRV RFLLGPMEGS EEKELTLTAT SVPSFINHPL VCGPAFAHLK VGVGHRLDAQ ASGVLVLGVG HGCRLLTDMY NAHLTKDYTV RGLLGKATDD FREDGRLVEK TTYDHVTREK LDRILAVIQG SHQKALVMYS NLDLKTQEAY EMAVRGLIRP MNKSPMLITG IRCLYFAPPE FLLEVQCMHE TQKELRKLVH EIGLELKTTA VCTQVRRTRD GFFTLDSALL RTQWDLTNIQ DAIRAATPQV AAELEKSLSP GLDTKQLPSP GWSWDSQGPS STLGLERGAG Q
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分子量
36.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRUB2, a member of the TRUB (tRNA and RNA binding) family, is a protein involved in RNA metabolism, particularly in the regulation of tRNA stability and maturation processes. Research has highlighted its role in maintaining the integrity of the cellular environment by influencing tRNA modifications and processing, ultimately impacting protein synthesis. Given the critical importance of tRNA in translation and its potential connection to various diseases, including cancer and genetic disorders, understanding TRUB2’s function and mechanism has become a focal point for molecular biology studies. Scientists have initiated the characterization of TRUB2 through recombinant protein techniques, enabling the analysis of its structure-function relationship. By producing TRUB2 in a controlled laboratory setting, researchers aim to elucidate its biochemical properties, interaction with other cellular components, and regulatory pathways. This research not only sheds light on fundamental cellular processes but also opens avenues for potential therapeutic targets by manipulating TRUB2 activity in disease contexts. The insights gained from the study of TRUB2 might contribute to the broader understanding of RNA biology and its implications in health and disease, highlighting the significance of this protein in both basic science and clinical applications. Continued exploration of TRUB2's roles and regulatory mechanisms is essential for uncovering new strategies in RNA-related therapies and enhancing our grasp of translational control in various biological systems.
