Cat: PA1000-8420

Recombinant Human Viperin Protein,His

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Analytical Data

  • Gene name

    Viperin

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Viperin;CIG5;S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8WXG1

  • Expression Region

    1-361aa

  • AA Sequence

    MWVLTPAAFA GKLLSVFRQP LSSLWRSLVP LFCWLRATFW LLATKRRKQQ LVLRGPDETK EEEEDPPLPT TPTSVNYHFT RQCNYKCGFC FHTAKTSFVL PLEEAKRGLL LLKEAGMEKI NFSGGEPFLQ DRGEYLGKLV RFCKVELRLP SVSIVSNGSL IRERWFQNYG EYLDILAISC DSFDEEVNVL IGRGQGKKNH VENLQKLRRW CRDYRVAFKI NSVINRFNVE EDMTEQIKAL NPVRWKVFQC LLIEGENCGE DALREAERFV IGDEEFERFL ERHKEVSCLV PESNQKMKDS YLILDEYMRF LNCRKGRKDP SKSILDVGVE EAIKFSGFDE KMFLKRGGKY IWSKADLKLD W

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

Viperin, an interferon-stimulated gene (ISG), plays a crucial role in the innate immune response against viral infections. Discovered in the context of antiviral defense, Viperin is known for its ability to inhibit the replication of various viruses, including enveloped viruses such as HIV, West Nile virus, and influenza. Its mechanism of action involves the alteration of lipid metabolism, leading to the production of specific metabolites that interfere with viral life cycles. The recombinant expression of Viperin provides a valuable tool for studying its antiviral properties, molecular mechanisms, and potential therapeutic applications. Researchers aim to better understand Viperin's structure-function relationships and the signaling pathways involved in its induction and activity. This research is critical not only for elucidating Viperin's role in immune responses but also for developing novel antiviral strategies and therapeutics in the face of emerging infectious diseases. As viral threats continue to evolve, the study of Viperin and its recombinantly expressed variants may offer new insights into host defense mechanisms and pave the way for innovative approaches in combating viral pathogens.

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