Analytical Data
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Gene name
ZNF443
- Application
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Alternative Names
ZNF443; Zinc finger Protein 443; Krueppel-type zinc finger Protein ZK1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y2A4
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Expression Region
1-671 aa
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AA Sequence
MASVALEDVA VNFTREEWAL LGPCQKNLYK DVMQETIRNL DCVVMKWKDQ NIEDQYRYPR KNLRCRMLER FVESKDGTQC GETSSQIQDS IVTKNTLPGV GPCESSMRGE KVMGHSSLNC YIRVGAGHKP HEYHECGEKP DTHKQRGKAF SYHNSFQTHE RLHTGKKPYD CKECGKSFSS LGNLQRHMAV QRGDGPYKCK LCGKAFFWPS LLHMHERTHT GEKPYECKQC SKAFSFYSSY LRHERTHTGE KPYECKQCSK AFPFYSSYLR HERTHTGEKP YKCKQCSKAF PDSSSCLIHE RTHTGEKPYT CKQCGKAFSV SGSLQRHETT HSAEKPYACQ QCGKAFHHLG SFQRHMIRHT GNGPHKCKIC GKGFDCPSSL QSHERTHTGE KPYECKQCGK ALSHRSSFRS HMIMHTGDGP HKCKVCGKAF VYPSVFQRHE RTHTAEKPYK CKQCGKAYRI SSSLRRHETT HTGEKPYKCK LGKACIDFCS FQNHKTTHTG EKPYECKECG KAFSRFRYLS RHKRTHTGEK PYECKTCRKA FGHYDNLKVH ERIHSGEKPY ECKECGKAFS WLTCFLRHER IHMREKSYEC PQCGKAFTHS RFLQGHEKTH TGENPYECKE CGKAFASLSS LHRHKKTHWK KTHTGENPYE CKECGKAFAS LSSLHRHKKT H
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Molecular Weight
77.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF443, a member of the zinc finger protein family, has garnered attention in recent studies due to its potential role in gene regulation and cellular processes. Researchers have identified ZNF443 as a transcription factor that may influence the expression of multiple genes, particularly those involved in cellular growth and differentiation. Its unique structure, characterized by multiple zinc finger motifs, allows it to interact with DNA and other proteins, thereby modulating various signaling pathways. Recent investigations have suggested that ZNF443 may be implicated in certain diseases, including cancer, where its regulatory functions could contribute to tumorigenesis and metastasis. Consequently, the study of ZNF443 recombinant proteins has become a focal point in understanding its biological functions and therapeutic potential. By producing and analyzing ZNF443 recombinant proteins, researchers aim to elucidate its specific interactions and mechanisms at the molecular level. This knowledge could lead to novel applications in targeted therapies, as manipulating ZNF443 functions might prove beneficial in managing diseases marked by dysregulated gene expression. Overall, the research surrounding ZNF443 is pivotal in uncovering its significance in health and disease, providing insight into the intricate interplay between transcription factors and cellular dynamics.
