Analytical Data
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基因名
ZNF443
- Application
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别名
ZNF443; Zinc finger Protein 443; Krueppel-type zinc finger Protein ZK1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2A4
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表达区间
1-671 aa
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氨基酸序列
MASVALEDVA VNFTREEWAL LGPCQKNLYK DVMQETIRNL DCVVMKWKDQ NIEDQYRYPR KNLRCRMLER FVESKDGTQC GETSSQIQDS IVTKNTLPGV GPCESSMRGE KVMGHSSLNC YIRVGAGHKP HEYHECGEKP DTHKQRGKAF SYHNSFQTHE RLHTGKKPYD CKECGKSFSS LGNLQRHMAV QRGDGPYKCK LCGKAFFWPS LLHMHERTHT GEKPYECKQC SKAFSFYSSY LRHERTHTGE KPYECKQCSK AFPFYSSYLR HERTHTGEKP YKCKQCSKAF PDSSSCLIHE RTHTGEKPYT CKQCGKAFSV SGSLQRHETT HSAEKPYACQ QCGKAFHHLG SFQRHMIRHT GNGPHKCKIC GKGFDCPSSL QSHERTHTGE KPYECKQCGK ALSHRSSFRS HMIMHTGDGP HKCKVCGKAF VYPSVFQRHE RTHTAEKPYK CKQCGKAYRI SSSLRRHETT HTGEKPYKCK LGKACIDFCS FQNHKTTHTG EKPYECKECG KAFSRFRYLS RHKRTHTGEK PYECKTCRKA FGHYDNLKVH ERIHSGEKPY ECKECGKAFS WLTCFLRHER IHMREKSYEC PQCGKAFTHS RFLQGHEKTH TGENPYECKE CGKAFASLSS LHRHKKTHWK KTHTGENPYE CKECGKAFAS LSSLHRHKKT H
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分子量
77.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF443, a member of the zinc finger protein family, has garnered attention in recent studies due to its potential role in gene regulation and cellular processes. Researchers have identified ZNF443 as a transcription factor that may influence the expression of multiple genes, particularly those involved in cellular growth and differentiation. Its unique structure, characterized by multiple zinc finger motifs, allows it to interact with DNA and other proteins, thereby modulating various signaling pathways. Recent investigations have suggested that ZNF443 may be implicated in certain diseases, including cancer, where its regulatory functions could contribute to tumorigenesis and metastasis. Consequently, the study of ZNF443 recombinant proteins has become a focal point in understanding its biological functions and therapeutic potential. By producing and analyzing ZNF443 recombinant proteins, researchers aim to elucidate its specific interactions and mechanisms at the molecular level. This knowledge could lead to novel applications in targeted therapies, as manipulating ZNF443 functions might prove beneficial in managing diseases marked by dysregulated gene expression. Overall, the research surrounding ZNF443 is pivotal in uncovering its significance in health and disease, providing insight into the intricate interplay between transcription factors and cellular dynamics.
