Analytical Data
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基因名
TRIM54
- Application
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别名
MURF 3; MuRF; MURF-3; MuRF3; Muscle specific RING finger Protein 3; Muscle specific RING finger Protein; Muscle specific RING finger Protein homolog; Muscle-specific RING finger Protein 3; Muscle-specific RING finger Protein; RING finger Protein 30; RNF30; TRI54_HUMAN; TRIM 54; Trim54; Tripartite motif containing 54 ; Tripartite motif containing Protein 54; Tripartite motif-containing Protein 54
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYV2
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表达区间
1-358 aa
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氨基酸序列
MNFTVGFKPL LGDAHSMDNL EKQLICPICL EMFSKPVVIL PCQHNLCRKC ANDVFQASNP LWQSRGSTTV SSGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESSRPLHSKA EQHLMCEEHE EEKINIYCLS CEVPTCSLCK VFGAHKDCEV APLPTIYKRQ KSELSDGIAM LVAGNDRVQA VITQMEEVCQ TIEDNSRRQK QLLNQRFESL CAVLEERKGE LLQALAREQE EKLQRVRGLI RQYGDHLEAS SKLVESAIQS MEEPQMALYL QQAKELINKV GAMSKVELAG RPEPGYESME QFTVRVEHVA EMLRTIDFQP GASGEEEEVA PDGEEGSAGP EEERPDGP
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分子量
40.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRIM54, a member of the tripartite motif (TRIM) protein family, has garnered attention due to its potential roles in various biological processes, including cell proliferation, differentiation, and host defense. This protein is characterized by its RING finger, B-box, and coiled-coil domain structures, which are essential for its E3 ubiquitin ligase activity, enabling it to regulate protein degradation and stability. Research has indicated that TRIM54 may be involved in immune responses, particularly in the context of viral infections and inflammation, suggesting its importance in disease pathogenesis. Additionally, TRIM54 has been implicated in cancer biology, where its altered expression can influence tumor growth and progression. Understanding the molecular mechanisms underlying TRIM54's actions is crucial for elucidating its functional roles in health and disease. The potential therapeutic implications of modulating TRIM54 activity make it a compelling target for further investigation, driving research efforts to explore its applications in developing new treatment strategies for various conditions, including cancers and autoimmune disorders. Thus, the characterization of TRIM54 recombinant protein is not only vital for basic biological research but also holds promise for clinical advancements in treating diseases associated with its dysregulation.
