Analytical Data
-
Gene name
TRIM55
- Application
-
Alternative Names
MURF 2; MURF-2; MuRF2; Muscle specific ring finger 2; Muscle specific RING finger Protein 2; Muscle-specific RING finger Protein 2; RING finger Protein 29; RNF 29; RNF29; TRI55_HUMAN; TRIM 55; Trim55; Tripartite motif containing 55; Tripartite motif containing Protein 55; Tripartite motif-containing Protein 55
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BYV6
-
Expression Region
1-548 aa
-
AA Sequence
MSASLNYKSF SKEQQTMDNL EKQLICPICL EMFTKPVVIL PCQHNLCRKC ASDIFQASNP YLPTRGGTTM ASGGRFRCPS CRHEVVLDRH GVYGLQRNLL VENIIDIYKQ ESTRPEKKSD QPMCEEHEEE RINIYCLNCE VPTCSLCKVF GAHKDCQVAP LTHVFQRQKS ELSDGIAILV GSNDRVQGVI SQLEDTCKTI EECCRKQKQE LCEKFDYLYG ILEERKNEMT QVITRTQEEK LEHVRALIKK YSDHLENVSK LVESGIQFMD EPEMAVFLQN AKTLLKKISE ASKAFQMEKI EHGYENMNHF TVNLNREEKI IREIDFYRED EDEEEEEGGE GEKEGEGEVG GEAVEVEEVE NVQTEFPGED ENPEKASELS QVELQAAPGA LPVSSPEPPP ALPPAADAPV TQGEVVPTGS EQTTESETPV PAAAETADPL FYPSWYKGQT RKATTNPPCT PGSEGLGQIG PPGSEDSNVR KAEVAAAAAS ERAAVSGKET SAPAATSQIG FEAPPLQGQA AAPASGSGAD SEPARHIFSF SWLNSLNE
-
Molecular Weight
60.4 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRIM55, a member of the tripartite motif (TRIM) protein family, has garnered attention in recent years due to its potential roles in regulating various cellular processes, including apoptosis, autophagy, and inflammation. Research indicates that TRIM55 is involved in the modulation of immune responses and may influence the development of cancer through its effects on cell proliferation and differentiation. Initially identified for its ability to interact with and regulate various signaling pathways, TRIM55 has been explored as a key player in maintaining cellular homeostasis. Disturbances in TRIM55 expression or function have been linked to several pathologies, including tumors and autoimmune diseases, suggesting that it may serve as a biomarker or therapeutic target. Recent studies employing recombinant TRIM55 protein have provided insights into its structural and functional properties, revealing its potential as a novel target for drug discovery. Consequently, understanding TRIM55's mechanisms of action and interactions with other cellular components is crucial for elucidating its role in health and disease, paving the way for the development of innovative therapeutic strategies aimed at manipulating its activity for clinical benefit.
