Cat: PAX2000-12791

Recombinant Human ZNF259 Protein,His

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Analytical Data

  • Gene name

    ZNF259

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    MGC110983; Zinc finger Protein 259; Zinc finger Protein ZPR1; ZNF 259; ZNF259; ZPR1; ZPR1_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O75312

  • Expression Region

    1-459 aa

  • AA Sequence

    MAASGAVEPG PPGAAVAPSP APAPPPAPDH LFRPISAEDE EQQPTEIESL CMNCYCNGMT RLLLTKIPFF REIIVSSFSC EHCGWNNTEI QSAGRIQDQG VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER YKRTFDQNEE LGLNDMKTEG YEAGLAPQR

  • Molecular Weight

    50.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ZNF259, a member of the zinc finger protein family, is primarily known for its role in gene regulation and its association with various biological processes, including lipid metabolism. Research indicates that ZNF259 may interact with specific transcription factors to modulate the expression of genes involved in cholesterol and lipid homeostasis. Genetic studies have highlighted ZNF259 as a candidate gene linked to lipid traits, suggesting its potential role in metabolic disorders such as dyslipidemia and atherosclerosis. The protein has garnered interest due to its localization on chromosome 19, near the genes associated with lipid metabolism, making it a significant focus in studies exploring the genetic basis of cardiovascular diseases. By developing recombinant ZNF259 protein, researchers aim to elucidate its structural and functional properties, enabling a deeper understanding of its mechanistic roles in cellular processes. The insights gained from this research could pave the way for therapeutic interventions targeting lipid-related diseases, underscoring the importance of ZNF259 in health and disease.

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