Analytical Data
-
Gene name
ZNF257
- Application
-
Alternative Names
BMZF 4; BMZF-4; BMZF4; Bone marrow zinc finger 4; Zinc finger Protein 257; ZN257_HUMAN; ZNF257
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y2Q1
-
Expression Region
1-563 aa
-
AA Sequence
MGPLTIRDVT VEFSLEEWHC LDTAQQNLYR DVMLENYRNL VFLGIAVSKP DLITCLEQGK EPCNMKRHEM VAKPPVMCSH IAEDLCPERD IKYFFQKVIL RRYDKCEHEN LQLRKGCKSV DECKVCKGGY NGLNQCLITT QSKMYQCDKY VKVFYKFSNS DRHKIRHTEK KTCKCKECGK SFCMLSQLTR HKRIHIRENS HKCEECGKAF NQSSALTRHK MTHTGEKPYK CEECGKAFNR SSHLTQHKVI HTREKPYKCE ECGKAFNRSS HITQHKRIHN REKPFKYDEC CKAFKWSSAL TTLTQHKRIH TGEKPYKCEE CGKAFNQSSA LTRHKMIHTG EKPFQCEECG KAFNRSSHLT QHKIIHTKEK PYKCEECGKA FNRSSHLTKH KRIHTREKAY KCDEYCKAFN WSSALTTLTQ HKIIHTGEKP YKCEECGKAF NRSSYLIRHK IIHTGEKPYK CEECGKAFNQ SSHLTQHKII HTGEKPYKCE ECGKAFNRSS HLSQHKIIHT GEKPYKCEEC GKPFNRFSYL TVHKRIHAGE NPNKYEECGK ACNHSSNLTK HNS
-
Molecular Weight
65.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF257, a member of the zinc finger protein family, has garnered significant interest in recent years due to its potential role in various biological processes and disease mechanisms. Characterized by its distinct zinc finger motifs, ZNF257 is believed to be involved in DNA binding and transcriptional regulation, which are crucial for maintaining cellular homeostasis and orchestrating gene expression in response to environmental cues. Recent studies have indicated that dysregulation of ZNF257 may be linked to several conditions, including cancer and metabolic disorders, highlighting its importance as a potential biomarker and therapeutic target. Furthermore, research has shown that ZNF257 may interact with key cellular pathways, influencing processes such as cell proliferation and differentiation. The recombinant expression of ZNF257 allows researchers to explore its functional roles in greater depth, facilitating the investigation of its interactions with other proteins and its impact on gene regulation. Understanding the intricate mechanisms underlying ZNF257 function could pave the way for novel treatments aimed at correcting its dysregulation in various diseases, making it a compelling focus for future studies in molecular biology and therapeutic development.
