Analytical Data
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基因名
PLAGL1
- Application
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别名
PLAGL1；LOT1；ZAC；Zinc finger Protein PLAGL1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UM63
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表达区间
1-463aa
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氨基酸序列
MATFPCQLCG KTFLTLEKFT IHNYSHSRER PYKCVQPDCG KAFVSRYKLM RHMATHSPQK SHQCAHCEKT FNRKDHLKNH LQTHDPNKMA FGCEECGKKY NTMLGYKRHL ALHAASSGDL TCGVCALELG STEVLLDHLK AHAEEKPPSG TKEKKHQCDH CERCFYTRKD VRRHLVVHTG CKDFLCQFCA QRFGRKDHLT RHTKKTHSQE LMKESLQTGD LLSTFHTISP SFQLKAAALP PFPLGASAQN GLASSLPAEV HSLTLSPPEQ AAQPMQPLPE SLASLHPSVS PGSPPPPLPN HKYNTTSTSY SPLASLPLKA DTKGFCNISL FEDLPLQEPQ SPQKLNPGFD LAKGNAGKVN LPKELPADAV NLTIPASLDL SPLLGFWQLP PPATQNTFGN STLALGPGES LPHRLSCLGQ QQQEPPLAMG TVSLGQLPLP PIPHVFSAGT GSAILPHFHH AFR
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLAGL1, or Placentally Expressed Gene 1, is a zinc finger protein initially identified for its role in placental development and growth regulation. It has garnered interest due to its involvement in various biological processes, including cell proliferation, differentiation, and tumorigenesis. The dysregulation of PLAGL1 has been implicated in certain cancers, particularly in teratomas and Wilms tumors, where its overexpression may contribute to oncogenic transformation. Moreover, PLAGL1 functions as a transcription factor, modulating the expression of genes involved in critical cellular pathways. Researchers have increasingly focused on the recombinant production of PLAGL1 protein to facilitate detailed studies on its structure-function relationship, binding affinities, and interaction with other biomolecules. The recombinant protein is essential for elucidating the molecular mechanisms underlying its role in cancer biology and development. Understanding PLAGL1’s functional characteristics may lead to novel therapeutic strategies targeting its pathways in diseases where it is aberrantly expressed. Additionally, PLAGL1 has potential applications in biomedical research and biotechnology as a biomarker or a target for drug development, further emphasizing the need for high-quality recombinant protein for experimental purposes.
