Analytical Data
-
Gene name
TMSB4Y
- Application
-
Alternative Names
TMSB4Y; TB4YThymosin beta-4; Y-chromosomal
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O14604
-
Expression Region
1-44 aa
-
AA Sequence
MSDKPGMAEI EKFDKSKLKK TETQEKNPLS SKETIEQERQ AGES
-
Molecular Weight
5.0 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMSB4Y (Thymosin Beta-4 Y-Linked) is a member of the thymosin family of peptides that is primarily expressed in the male gonads and is encoded by the Y chromosome. Its role in cytoskeletal dynamics, cell migration, and tissue regeneration has garnered significant interest in the fields of developmental biology and regenerative medicine. Research has shown that TMSB4Y is involved in crucial cellular processes such as actin polymerization and the regulation of cell motility, which are vital for various physiological and pathological conditions, including wound healing and cancer metastasis. Additionally, being Y-linked, TMSB4Y is also a candidate for studies exploring the unique aspects of male-specific gene expression and its implications in gender-specific diseases and traits. The recombinant expression of TMSB4Y allows for the investigation of its functional properties and potential therapeutic applications. Understanding the molecular mechanisms and pathways influenced by TMSB4Y could lead to novel strategies in treating disorders associated with dysfunctional cellular migration and cytoskeletal abnormalities. As researchers continue to elucidate the precise roles and regulatory mechanisms of TMSB4Y, this protein presents opportunities for innovative biomedical applications targeting male health and related conditions. The ongoing studies into TMSB4Y not only highlight its importance in fundamental biology but also its potential translational implications in clinical settings.
