Analytical Data
-
基因名
EXOC3L4
- Application
-
别名
C14orf73; EX3L4_HUMAN; Exoc3l4; Exocyst complex component 3-like protein 4
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q17RC7
-
表达区间
1-722aa
-
氨基酸序列
MPSPQTDTPGPELQSPKEAEEPQTPAQGSRRTSSRKEPNAHRKDGTRLGLGSLRQAFSRASQRALTQVSKEDTGLFRRSSCSLFRSFRQALNDGPATGHSQATPEVPSGVMNGVSQQASTGAASEELKPEAEGKSVADLITERQLLAAFEQLLRLETLLVAEKASRTFEQDPTAFARRAMDVCLLYDGLAAEIGAIVRETLDSDGVDAAALAELARVVSAEEEAHPSPPDDGDFLRTPRRWRQHWEEAVRRSAQERVRRPGAGWAFGEAEGASGLAQLLAELGGLVRRDLQKVRQEVQPAYAAAGFPAWEVYLRAFHSAVAQRLQELARDARGCEQLYILLDWAANVYGSPDFLGAPGLALPAEPLPPLLAPDVWARLESDYTSFLEAKIASCFDSILQLEQSHWAAAEVPEVLQGLYQAPLSMDVHMLVAEHVKAAGAISAELEATTLRICTRALGLFVPRFEKAFLASEAVSEPHLGAYINACEELRTSLLSRFPGTQEELEKPLVTATCSFQKHLLQGLQRELQPLFRVVCTRDWLTQDWLHPLMDKVVTFAGHLQRVARPRAQETLQEVHRFVVREYLARALRPRERFRGMERMHGSQKMSLDAQAISDTFQGLGSEATWLDQAIQCVAEILGETYKDDIQRHLETLIRSYPDIRRDHILAILALRRLGRRRNQHLLQHTEDLLRAAAGAAGAEAPRGRVLFEEIKVPSAMAVLITCV
-
分子量
79.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The EXOC3L4 protein, a member of the exocyst complex, plays a crucial role in the trafficking of vesicles to the plasma membrane, essential for various cellular processes such as secretion, cell signaling, and maintaining cellular architecture. Research into EXOC3L4 has gained momentum due to its potential implications in several diseases, including cancer and neurodegenerative disorders. Understanding the functional mechanisms of EXOC3L4 can provide insights into how altered exocytic pathways contribute to disease progression. Additionally, the exploration of EXOC3L4 as a potential therapeutic target is becoming increasingly relevant, especially in the context of cancer therapies that exploit the precision of targeted delivery systems. Recombinant expression of EXOC3L4 allows for detailed structural and functional studies, facilitating the investigation of its interactions with other proteins and its role in the exocyst complex. This research is vital for elucidating the pathways of cellular communication and could lead to the development of novel therapeutic strategies aimed at correcting the dysregulation of exocytosis associated with various pathological conditions. By advancing our understanding of EXOC3L4, we can pave the way for innovative approaches to treatment and the potential discovery of biomarkers for early disease detection.
