Analytical Data
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Gene name
TMPRSS13
- Application
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Alternative Names
Membrane-type mosaic serine protease;Mosaic serine protease
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BYE2
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Expression Region
187-586 aa
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AA Sequence
QFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL
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Molecular Weight
51.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMPRSS13, a member of the transmembrane protease serine 13 family, has garnered attention in recent years due to its potential roles in various physiological and pathological processes. This serine protease, which is primarily expressed in human tissues, is implicated in the activation of several type II transmembrane proteins, influencing cellular signaling pathways and contributing to processes such as inflammation, cell migration, and viral entry. Preliminary studies suggest that TMPRSS13 may play a significant role in immune responses and could be involved in the pathogenesis of certain diseases, including cancer and viral infections. The investigation of TMPRSS13 recombinant proteins aims to elucidate their enzymatic activity, substrate specificity, and broader functional roles in human health. Furthermore, understanding the molecular mechanisms by which TMPRSS13 operates could lead to novel therapeutic strategies targeting its activity, potentially providing new avenues for treatment in diseases linked with dysregulated proteolytic processes. As research in this area continues to evolve, TMPRSS13 reconstitution studies are expected to shed light on its diverse biological functions and significance in translational medicine.
