Analytical Data
-
基因名
EXOC3L1
- Application
-
别名
EXOC3L1; EXOC3LExocyst complex component 3-like protein; Protein Jiangli
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q86VI1
-
表达区间
1-746aa
-
氨基酸序列
MDSAAKDEMQ PALSPGPEWP EQERAEQLAR GAALKWASGI FYRPEQLARL GQYRSREVQR TCSLESRLKS VMQSYLEGVQ TGVWQLAQAI EVVQGTREAL SQARGLLQGM SQALQTLEPL RERVAQHKQL QALSHLLPRL RAVPAAVSHT QTLIDGQQFL EAYVSLRELE QLREDTWAPL GGLELPVFQG LDLLFEALGQ AVEAAAGAAG KLAREDPALL VAAVRVAEVE TGRTTPLGQV PRDWRQRCLR ALQEGLEQAH FGSPLLPAPG ALPGWLEALR VALPVELATA EALVAPCCPP QYNVVQLWAH TLHSGLRRSL QNLLAGPELE AADAFALLHW ALHVYLGQEM MGSLELGPEA DVSQLEPLLT LENIEQLEAT FVANIQASVS QWLQNALDGE VAEWGREHGP NTDPSGSYYS PMPAIVLQIL EENIRVASLV SESLQQRVHG MALSELGTFL RSFSDALIRF SRDHFRGKSM APHYVPYLLA ALNHKSALSS SVSVLQLDGA PSGALAPVEA ALDELQRRIY RLVLEALQAE LQPLFADLPS RQWLSSPELL QSVCERTGRF CRDFWRVRNP TVQLLLAEAE RAVVLQYLSA LMQGRLVCRG ADERTQAAER LRHDAAQLQQ LFLSLGLEEN AHCAPVLLAL RELLNLRDPA LLGLEVAGLR QQFPDVSEDH VSALLGLRGD LSREQHLAAL SSLQAALPPS PRASRRVLFS LVPAPALAPA SCLPSGSCAR ALLLAE
-
分子量
81.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EXOC3L1, a member of the exocyst complex, plays a crucial role in the regulation of membrane trafficking, particularly in the context of cellular exocytosis. The exocyst is a conserved protein complex that facilitates the tethering of secretory vesicles to the plasma membrane, a vital process for various cellular functions, including neurotransmission, hormone secretion, and cell migration. Disruptions in exocyst function have been implicated in several diseases, including cancer and neurodegenerative disorders. Research on EXOC3L1 is particularly important due to its potential involvement in regulating these pathways and its interactions with other proteins within the exocyst complex. Recent studies have focused on elucidating the structure and function of EXOC3L1 through the development of recombinant protein systems. By producing and characterizing recombinant EXOC3L1, researchers aim to understand its molecular interactions, regulatory mechanisms, and the impact of specific mutations associated with disease states. This knowledge is essential for developing therapeutic strategies targeting exocyst dysfunction and delineating the complex signaling pathways involved in cellular exocytosis. Overall, the study of EXOC3L1 and its role in the exocyst complex holds promise for advancing our understanding of cellular dynamics and its implications in health and disease.
