Cat: PAX2000-12784

Recombinant Human ZNF23 Protein,His

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Analytical Data

  • Gene name

    ZNF23

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZNF23; KOX16; ZNF359; ZNF612Zinc finger Protein 23; Zinc finger Protein 359; Zinc finger Protein 612; Zinc finger Protein KOX16

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P17027

  • Expression Region

    1-643 aa

  • AA Sequence

    MLENYGNVAS LGFPLLKPAV ISQLEGGSEL GGSSPLAAGT GLQGLQTDIQ TDNDLTKEMY EGKENVSFEL QRDFSQETDF SEASLLEKQQ EVHSAGNIKK EKSNTIDGTV KDETSPVEEC FFSQSSNSYQ CHTITGEQPS GCTGLGKSIS FDTKLVKHEI INSEERPFKC EELVEPFRCD SQLIQHQENN TEEKPYQCSE CGKAFSINEK LIWHQRLHSG EKPFKCVECG KSFSYSSHYI THQTIHSGEK PYQCKMCGKA FSVNGSLSRH QRIHTGEKPY QCKECGNGFS CSSAYITHQR VHTGEKPYEC NDCGKAFNVN AKLIQHQRIH TGEKPYECNE CGKGFRCSSQ LRQHQSIHTG EKPYQCKECG KGFNNNTKLI QHQRIHTGEK PYECTECGKA FSVKGKLIQH QRIHTGEKPY ECNECGKAFR CNSQFRQHLR IHTGEKPYEC NECGKAFSVN GKLMRHQRIH TGEKPFECNE CGRCFTSKRN LLDHHRIHTG EKPYQCKECG KAFSINAKLT RHQRIHTGEK PFKCMECEKA FSCSSNYIVH QRIHTGEKPF QCKECGKAFH VNAHLIRHQR SHTGEKPFRC VECGKGFSFS SDYIIHQTVH TWKKPYMCSV CGKAFRFSFQ LSQHQSVHSE GKS

  • Molecular Weight

    73 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ZNF23 (Zinc Finger Protein 23) is a member of the zinc finger protein family, which plays crucial roles in transcriptional regulation and cellular processes. The research surrounding ZNF23 has gained momentum due to its potential implications in various biological functions, including gene expression, cell differentiation, and development. Recent studies have suggested that ZNF23 may be involved in the regulation of oncogenes and tumor suppressor genes, indicating a possible connection to cancer biology and therapeutic targets. Its ability to interact with DNA and other regulatory proteins positions ZNF23 as a key player in the transcriptional landscape of various cell types. Moreover, ZNF23 has been implicated in the regulation of the immune response and neurodevelopmental processes, highlighting its multifaceted role in human health. Due to these significant functionalities, researchers have focused on producing recombinant ZNF23 proteins to elucidate its mechanisms of action, identify interaction partners, and explore its potential as a biomarker or therapeutic target. The generation of ZNF23 recombinant proteins allows for detailed biochemical assays and structural studies, providing insights into its role in pathophysiological contexts. This work not only enhances our understanding of ZNF23's biological significance but also paves the way for developing novel strategies in treating diseases associated with its dysregulation.

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