Cat: PA1000-8308

Recombinant Human DPYSL3 Protein,His

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Analytical Data

  • Gene name

    DPYSL3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DPYSL3;CRMP4;DRP3;ULIP;Dihydropyrimidinase-related Protein 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q14195

  • Expression Region

    1-570aa

  • AA Sequence

    MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLI VPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGG TTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQ EVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAE NGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL YVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAA FVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTA IPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGR ISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQG KIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYD GPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVR SASKRIVAPPGGRSNITSLS

  • Molecular Weight

    88 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

DPYSL3 (Dipeptidyl Peptidase I-Like 3) is a member of the dipeptidyl peptidase (DPP) family, which plays a crucial role in various biological processes, including neuronal development, cell migration, and signaling pathways. Research has demonstrated that DPYSL3 is involved in the regulation of cytoskeletal dynamics, influencing axon growth and guidance in neurons. Dysregulation of DPYSL3 expression has been implicated in several neurological disorders, making it a target of interest for therapeutic intervention. Additionally, its role in cellular response mechanisms to stress and injury elevates its significance in studies focusing on neurodegenerative diseases. Understanding the expression patterns, functional mechanisms, and potential interactions of DPYSL3 can provide key insights into its contribution to cellular homeostasis and disease pathology. Given its central role in critical neurobiological processes, the recombinant expression of DPYSL3 protein facilitates detailed investigations into its structural and functional properties, enabling researchers to explore its therapeutic potential further. The ongoing studies aim to elucidate the molecular mechanisms governed by DPYSL3 and its implications in health and disease, thereby enhancing our understanding of its biological significance.

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