Analytical Data
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Gene name
ZNF223
- Application
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Alternative Names
ZNF223; Zinc finger Protein 223
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UK11
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Expression Region
1-482 aa
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AA Sequence
MTMSKEAVTF KDVAVVFTEE ELGLLDLAQR KLYRDVMLEN FRNLLSVGHQ PFHRDTFHFL REEKFWMMDI ATQREGNSGG KIQPEMKTFP EAGPHEGWSC QQIWEEIASD LTRPQDSTIK SSQFFEQGDA HSQVEEGLSI MHTGQKPSNC GKCKQSFSDM SIFDLPQQIR SAEKSHSCDE CGKSFCYISA LHIHQRVHLG EKLFKCDVCG KEFSQSLHLQ THQRVHTGEK PFKCEQCGRG FRCRSALTVH CKLHMGEKHY NCEACGRAFI HDFQLQKHQR IHTGEKPFKC EICSVSFRLR SSLNRHCVVH TGKKPNSTGE YGKGFIRRLD LCKHQTIHTG EKPYNCKECG KSFRRSSYLL IHQRVHTGEK PYKCDKCGKS YITKSGLDLH HRAHTGERPY NCDDCGKSFR QASSILNHKR LHCRKKPFKC EDCGKKLVYR SYRKDQQKNH SGENPSKCED CGKRYKRRLN LDIILSLFLN DT
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Molecular Weight
55.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF223 (Zinc Finger Protein 223) is a member of the zinc finger protein family, which is characterized by the presence of zinc finger motifs that facilitate DNA binding and gene regulation. These proteins are integral in various biological processes, including embryonic development, cell differentiation, and responses to environmental stimuli. Recent studies have indicated that ZNF223 plays a crucial role in modulating gene expression, particularly in the context of immune response and cancer biology. Dysregulation of ZNF223 has been linked to several pathological conditions, including tumoral processes, where it may impact cellular proliferation and apoptosis. The recombinant production of ZNF223 protein enables researchers to investigate its structure-function relationship and its interaction with DNA and other proteins. Such studies can elucidate the underlying molecular mechanisms that govern its role in transcriptional regulation and cellular signaling pathways. Understanding the functional dynamics of ZNF223 through recombinant protein technology is essential for exploring potential therapeutic targets, especially in cancer treatment, where manipulating its activity could offer novel strategies for intervention. Thus, ZNF223 continues to be a focal point of research in molecular biology and oncology, offering insights into the regulatory networks that influence cell behavior and disease progression.
