Analytical Data
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基因名
ZNF219
- Application
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别名
Zinc finger Protein 219; ZN219_HUMAN; ZNF219
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P2Y4
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表达区间
1-722 aa
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氨基酸序列
MEGSRPRAPS GHLAPSPPAF DGELDLQRYS NGPAVSAGSL GMGAVSWSES RAGERRFPCP VCGKRFRFNS ILALHLRAHP GAQAFQCPHC GHRAAQRALL RSHLRTHQPE RPRSPAARLL LELEERALLR EARLGRARSS GGMQATPATE GLARPQAPSS SAFRCPYCKG KFRTSAERER HLHILHRPWK CGLCSFGSSQ EEELLHHSLT AHGAPERPLA ATSAAPPPQP QPQPPPQPEP RSVPQPEPEP EPEREATPTP APAAPEEPPA PPEFRCQVCG QSFTQSWFLK GHMRKHKASF DHACPVCGRC FKEPWFLKNH MKVHASKLGP LRAPGPASGP ARAPQPPDLG LLAYEPLGPA LLLAPAPTPA ERREPPSLLG YLSLRAGEGR PNGEGAEPGP GRSFGGFRPL SSALPARARR HRAEEPEEEE EVVEAEEETW ARGRSLGSLA SLHPRPGEGP GHSASAAGAQ ARSTATQEEN GLLVGGTRPE GGRGATGKDC PFCGKSFRSA HHLKVHLRVH TGERPYKCPH CDYAGTQSGS LKYHLQRHHR EQRSGAGPGP PPEPPPPSQR GSAPQSGAKP SPQPATWVEG ASSPRPPSSG AGPGSRRKPA SPGRTLRNGR GGEAEPLDLS LRAGPGGEAG PGGALHRCLF CPFATGAPEL MALHLQVHHS RRARGRRPPQ ADASPPYARV PSGETPPSPS QEGEEGSGLS RPGEAGLGGQ ER
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分子量
76.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF219 is a member of the zinc finger protein family, which plays a crucial role in various biological processes, including gene regulation, cell differentiation, and development. Due to its functional similarities with other zinc finger proteins, ZNF219 has garnered interest in the context of disease mechanisms, particularly in cancer and genetic disorders. The gene encoding ZNF219 has been implicated in transcriptional regulation, with studies suggesting its involvement in pathways that govern cell proliferation and survival. The protein’s unique structure, characterized by multiple zinc finger motifs, allows it to bind to specific DNA sequences, thereby modulating the expression of target genes. Research has also indicated that ZNF219 may interact with other regulatory proteins, influencing signaling pathways and cellular responses. As such, recombinant ZNF219 protein has been the focus of studies aimed at elucidating its functional roles and potential therapeutic applications. Understanding the biochemical properties and interactions of ZNF219 could provide insights into its contribution to health and disease, paving the way for novel strategies in drug development and targeted therapies. Furthermore, the generation of recombinant ZNF219 may enable high-throughput screening of small molecules that can disrupt its function, potentially leading to new treatment options for conditions associated with dysregulation of this important transcription factor.
