Cat: PAX2000-12045

Recombinant Human TMEM50B Protein,GST

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Analytical Data

  • Gene name

    TMEM50B

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TMEM50B; C21orf4; UNQ167/PRO193; Transmembrane Protein 50B; HCV p7-trans-regulated Protein 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P56557

  • Expression Region

    1-158 aa

  • AA Sequence

    MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT

  • Molecular Weight

    44.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TMEM50B (Transmembrane Protein 50B) is a relatively understudied protein that belongs to the family of membrane proteins involved in various cellular processes. Recent research has highlighted its potential roles in endosomal trafficking, cellular stress responses, and signal transduction pathways. The protein's unique structure and membrane localization suggest that it may play a crucial role in the maintenance of cellular homeostasis and the regulation of intracellular signaling networks. Given its involvement in essential biological processes, understanding TMEM50B's functional mechanisms has significant implications for various fields, including cancer research, neurobiology, and metabolic disorders. Recombinant TMEM50B protein production enables researchers to investigate its biochemical properties, interactions with other proteins, and cellular localization, fostering a deeper understanding of its role in health and disease. Additionally, the availability of this protein could pave the way for exploring its potential as a therapeutic target or biomarker in various pathologies. As the scientific community continues to unravel the complexities of membrane proteins, TMEM50B stands out as a promising candidate for further exploration, ultimately contributing to the broader understanding of cellular dynamics and disease mechanisms.

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