Analytical Data
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基因名
TMEM17
- Application
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别名
TMEM17; Transmembrane Protein 17
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86X19
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表达区间
1-198 aa
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氨基酸序列
MELPDPVRQRLGNFSRAVFSDSNRTSPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLFLAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI
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分子量
49.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMEM17, a transmembrane protein, has garnered significant attention in recent years due to its potential roles in various biological processes and diseases. Initially identified as a protein with unknown function, subsequent studies have linked TMEM17 to crucial cellular functions, including ion transport, cell signaling, and membrane dynamics. Its expression is found in multiple tissues, suggesting a widespread influence, particularly in the nervous system and immune cells. Research indicates that TMEM17 may be implicated in the regulation of autophagy and apoptosis, processes essential for maintaining cellular homeostasis. Given its involvement in these critical functions, alterations in TMEM17 expression or function have been associated with various pathologies, including cancer and neurodegenerative disorders. As a result, the characterization of recombinant TMEM17 protein has become imperative for understanding its structure-function relationship and exploring its potential as a therapeutic target. The production of TMEM17 in recombinant systems enables detailed biochemical analyses, facilitating studies on its interactions and mechanisms of action. This research not only aims to elucidate the biological significance of TMEM17 but also to provide insights into its role in disease mechanisms, potentially leading to novel diagnostic and therapeutic strategies. Ultimately, understanding TMEM17's function could unlock new avenues in the treatment of diseases where its dysregulation plays a critical role.












