Analytical Data
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基因名
TMEM167B
- Application
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别名
TMEM167B; C1orf119; AD-020; Protein kish-B; Transmembrane Protein 167B
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRX6
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表达区间
1-74 aa
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氨基酸序列
MTNVYSLDGILVFGLLFVCTCAYFKKVPRLKTWLLSEKKGVWGVFYKAAVIGTRLHAAVAIACVVMAFYVLFIK
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分子量
34.54 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMEM167B, a member of the transmembrane protein family, has emerged as a subject of interest in the field of molecular biology and cell physiology due to its potential roles in cellular mechanisms and disease pathogenesis. Located in the endoplasmic reticulum, TMEM167B has been implicated in cellular processes such as protein folding, trafficking, and membrane dynamics. Recent studies have suggested that it may play a significant role in the modulation of autophagy and endosomal trafficking, which are crucial for maintaining cellular homeostasis. Mutations and dysregulation of TMEM167B have been linked to various diseases, including developmental disorders and neurodegenerative conditions, highlighting its potential as a therapeutic target. The production of recombinant TMEM167B protein provides a valuable tool for in-depth functional studies, allowing researchers to investigate its interactions, structural characteristics, and biological implications. By studying the recombinant version of this protein, scientists aim to elucidate its specific roles in cellular pathways and to explore its potential contributions to human health and disease, paving the way for novel therapeutic strategies.
