Analytical Data
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基因名
ZNF14
- Application
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别名
ZNF14; GIOT4; KOX6; Zinc finger Protein 14; Gonadotropin-inducible ovary transcription repressor 4; GIOT-4; Zinc finger Protein KOX6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17017
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表达区间
1-642 aa
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氨基酸序列
MDSVSFEDVA VNFTLEEWAL LDSSQKKLYE DVMQETFKNL VCLGKKWEDQ DIEDDHRNQG KNRRCHMVER LCESRRGSKC GETTSQMPNV NINKETFTGA KPHECSFCGR DFIHHSSLNR HMRSHTGQKP NEYQEYEKQP CKCKAVGKTF SYHHCFRKHE RTHTGVKPYE CKQCGKAFIY YQPFQRHERT HAGQKPYECK QCGKTFIYYQ SFQKHAHTGK KPYECKQCGK AFICYQSFQR HKRTHTGEKP YECKQCGKAF SCPTYFRTHE RTHTGEKPYK CKECGKAFSF LSSFRRHKRT HSGEKPYECK ECGKAFFYSA SFRAHVIIHT GARPYKCKEC GKAFNSSNSC RVHERTHIGE KPYECKRCGK SFSWSISLRL HERTHTGEKP YECKQCHKTF SFSSSLREHE TTHTGEKPYE CKQCGKTFSF SSSLQRHERT HNAEKPYECK QCGKAFRCSS YFRIHERSHT GEKPYECKQC GKVFIRSSSF RLHERTHTGE KPYECKLCGK TFSFSSSLRE HEKIHTGNKP FECKQCGKAF LRSSQIRLHE RTHTGEKPYQ CKQCGKAFIS SSKFRMHERT HTGEKPYRCK QCGKAFRFSS SVRIHERSHT GEKPYECKQC GKAFISSSHF RLHERTHMGE KV
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分子量
75.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF14, a member of the zinc finger protein family, plays a crucial role in various biological processes, including gene regulation, cellular differentiation, and development. Its repressive function in transcriptional regulation has garnered attention in studies related to cancer, where aberrant expression patterns of ZNF proteins have been implicated in tumorigenesis. Research on ZNF14 has revealed its involvement in specific signaling pathways, influencing cell growth and apoptosis. The study of ZNF14 recombinant proteins provides valuable insights into its structural and functional characteristics, allowing for the exploration of its interaction with DNA and other protein partners. Furthermore, understanding ZNF14's mechanisms can offer novel therapeutic strategies for diseases associated with its dysregulation. Recent advancements in recombinant protein technology have facilitated the production and purification of ZNF14, enabling biochemical assays and functional studies to elucidate its roles in health and disease. As researchers continue to investigate ZNF14's contributions to cellular functions, this protein holds potential as a biomarker and therapeutic target in oncology and other fields of medicine.
