Cat: PAX2000-12741

Recombinant Human ZNF14 Protein,His

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Analytical Data

  • Gene name

    ZNF14

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZNF14; GIOT4; KOX6; Zinc finger Protein 14; Gonadotropin-inducible ovary transcription repressor 4; GIOT-4; Zinc finger Protein KOX6

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P17017

  • Expression Region

    1-642 aa

  • AA Sequence

    MDSVSFEDVA VNFTLEEWAL LDSSQKKLYE DVMQETFKNL VCLGKKWEDQ DIEDDHRNQG KNRRCHMVER LCESRRGSKC GETTSQMPNV NINKETFTGA KPHECSFCGR DFIHHSSLNR HMRSHTGQKP NEYQEYEKQP CKCKAVGKTF SYHHCFRKHE RTHTGVKPYE CKQCGKAFIY YQPFQRHERT HAGQKPYECK QCGKTFIYYQ SFQKHAHTGK KPYECKQCGK AFICYQSFQR HKRTHTGEKP YECKQCGKAF SCPTYFRTHE RTHTGEKPYK CKECGKAFSF LSSFRRHKRT HSGEKPYECK ECGKAFFYSA SFRAHVIIHT GARPYKCKEC GKAFNSSNSC RVHERTHIGE KPYECKRCGK SFSWSISLRL HERTHTGEKP YECKQCHKTF SFSSSLREHE TTHTGEKPYE CKQCGKTFSF SSSLQRHERT HNAEKPYECK QCGKAFRCSS YFRIHERSHT GEKPYECKQC GKVFIRSSSF RLHERTHTGE KPYECKLCGK TFSFSSSLRE HEKIHTGNKP FECKQCGKAF LRSSQIRLHE RTHTGEKPYQ CKQCGKAFIS SSKFRMHERT HTGEKPYRCK QCGKAFRFSS SVRIHERSHT GEKPYECKQC GKAFISSSHF RLHERTHMGE KV

  • Molecular Weight

    75.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF14, a member of the zinc finger protein family, plays a crucial role in various biological processes, including gene regulation, cellular differentiation, and development. Its repressive function in transcriptional regulation has garnered attention in studies related to cancer, where aberrant expression patterns of ZNF proteins have been implicated in tumorigenesis. Research on ZNF14 has revealed its involvement in specific signaling pathways, influencing cell growth and apoptosis. The study of ZNF14 recombinant proteins provides valuable insights into its structural and functional characteristics, allowing for the exploration of its interaction with DNA and other protein partners. Furthermore, understanding ZNF14's mechanisms can offer novel therapeutic strategies for diseases associated with its dysregulation. Recent advancements in recombinant protein technology have facilitated the production and purification of ZNF14, enabling biochemical assays and functional studies to elucidate its roles in health and disease. As researchers continue to investigate ZNF14's contributions to cellular functions, this protein holds potential as a biomarker and therapeutic target in oncology and other fields of medicine.

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