Analytical Data
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基因名
ZNF12
- Application
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别名
ZNF12; GIOT3; KOX3; ZNF325; Zinc finger Protein 12; Gonadotropin-inducible ovary transcription repressor 3; GIOT-3; Zinc finger Protein 325; Zinc finger Protein KOX3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17014
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表达区间
1-697 aa
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氨基酸序列
MNKSLGPVSF KDVAVDFTQE EWQQLDPEQK ITYRDVMLEN YSNLVSVGYH IIKPDVISKL EQGEEPWIVE GEFLLQSYPD EVWQTDDLIE RIQEEENKPS RQTVFIETLI EERGNVPGKT FDVETNPVPS RKIAYKNSLC DSCEKCLTSV SEYISSDGSY ARMKADECSG CGKSLLHIKL EKTHPGDQAY EFNQNGEPYT LNEESLYQKI RILEKPFEYI ECQKAFQKDT VFVNHMEEKP YKWNGSEIAF LQMSDLTVHQ TSHMEMKPYE CSECGKSFCK KSKFIIHQRT HTGEKPYECN QCGKSFCQKG TLTVHQRTHT GEKPYECNEC GKNFYQKLHL IQHQRTHSGE KPYECSYCGK SFCQKTHLTQ HQRTHSGERP YVCHDCGKTF SQKSALNDHQ KIHTGVKLYK CSECGKCFCR KSTLTTHLRT HTGEKPYECN ECGKFFSRLS YLTVHYRTHS GEKPYECNEC GKTFYLNSAL MRHQRVHTGE KPYECNECGK LFSQLSYLTI HHRTHSGVKP YECSECGKTF YQNSALCRHR RIHKGEKPYE CYICGKFFSQ MSYLTIHHRI HSGEKPYECS ECGKTFCQNS ALNRHQRTHT GEKAYECYEC GKCFSQMSYL TIHHRIHSGE KPFECNECGK AFSRMSYLTV HYRTHSGEKP YECTECGKKF YHKSAFNSHQ RIHRRGNMNV IDVGRLL
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分子量
81.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF12, or Zinc Finger Protein 12, is a member of the zinc finger protein family, which plays critical roles in various biological processes, including transcriptional regulation, cell differentiation, and development. Research has shown that ZNF12 is involved in the regulation of gene expression, and its dysfunction has been associated with numerous diseases, including cancer. In recent years, scientists have increasingly focused on the recombinant expression of ZNF12 to study its functional properties, interactions with other proteins, and its role in signaling pathways. The creation of ZNF12 recombinant proteins enables researchers to investigate its structure-function relationship, particularly how its zinc finger motifs contribute to DNA binding and regulatory functions. Additionally, understanding the mechanisms underlying ZNF12's action may provide insights into potential therapeutic targets for diseases linked to its dysregulation. By employing techniques such as cloning, expression in various host systems, and purification, researchers aim to produce high-quality ZNF12 proteins for biochemical assays, structural studies, and functional analyses. This research is vital for elucidating the biological roles of ZNF12 and its potential implications in health and disease.
