Analytical Data
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Gene name
PTPLA
- Application
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Alternative Names
PTPLA；PTPLA；Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
B0YJ81
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Expression Region
1-288aa
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AA Sequence
MGRLTEAAAAGSGSRAAGWAGSPPTLLPLSPTSPRCAATMASSDEDGTNGGASEAGEDREAPGERRRLGVLATAWLTFYDIAMTAGWLVLAIAMVRFYMEKGTHRGLYKSIQKTLKFFQTFALLEIVHCLIGIVPTSVIVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVAWTVTEITRYSFYTFSLLDHLPYFIKWARYNFFIILYPVGVAGELLTIYAALPHVKKTGMFSIRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIVEKDD
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Molecular Weight
32.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPLA (protein tyrosine phosphatase-like A) is an important protein that has drawn significant attention in recent years due to its role in various biological processes and potential clinical implications. This protein, part of the protein tyrosine phosphatase (PTP) family, is involved in the regulation of cellular signaling pathways, cell differentiation, and proliferation. Dysregulation of PTPLA has been implicated in several diseases, including cancer and metabolic disorders. Given its crucial functions, researchers are focusing on the expression, purification, and characterization of recombinant PTPLA to better understand its biological activities and interactions. Using recombinant DNA technology allows for the production of PTPLA in larger quantities and with higher purity, facilitating more detailed studies. Such research may lead to the development of novel therapeutic strategies targeting PTPLA-related pathways, ultimately contributing to improved treatments for diseases associated with its dysfunction. The exploration of PTPLA's structural properties and enzymatic mechanisms could also provide insights into its role within the broader context of cell signaling and metabolic regulation, highlighting its importance in both basic and applied biomedical research.
