Analytical Data
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Gene name
TMED3
- Application
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Alternative Names
C15orf22; Integral type I Protein; Membrane Protein p24B; p24 family Protein gamma 4; p24 family Protein gamma-4; P24B; p24g4; p24gamma4; p26; Testis tissue sperm binding Protein Li 48e; Tmed3; TMED3_HUMAN; Transmembrane emp24 domain containing Protein 3; Transmembrane emp24 domain-containing Protein 3; Transmembrane p24 trafficking Protein 3; UNQ5357/PRO1078
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y3Q3
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Expression Region
1-217 aa
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AA Sequence
MGSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
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Molecular Weight
51.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMED3, also known as transmembrane emp24 domain-containing protein 3, plays a crucial role in the cellular transport system, particularly in the endoplasmic reticulum and Golgi apparatus, which are vital for protein processing and sorting. This protein is part of the EMP24/GP25L family, involved in vesicular transport and membrane trafficking. Research has shown that TMED3 is essential for the proper functioning of the secretory pathway and may influence the biogenesis of certain viral proteins, making it a point of interest in virology. Moreover, TMED3 has been implicated in various cellular processes, including apoptosis and the regulation of the immune response. Given its significance, understanding the structure and function of TMED3 through recombinant protein studies can provide insights into its mechanistic roles in health and disease, as well as its potential as a therapeutic target in conditions like cancer and viral infections. As the exploration of TMED3 continues, the production of recombinant TMED3 protein serves as a valuable tool for functional assays, structural analysis, and the development of novel therapeutic strategies.
