Analytical Data
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Gene name
ZMYND12
- Application
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Alternative Names
ZMYND12; Zinc finger MYND domain-containing Protein 12
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H0C1
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Expression Region
1-365 aa
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AA Sequence
MNVIYPLAVP KGRRLCCEVC EAPAERVCAA CTVTYYCGVV HQKADWDSIH EKICQLLIPL RTSMPFYNSE EERQHGLQQL QQRQKYLIEF CYTIAQKYLF EGKHEDAVPA ALQSLRFRVK LYGLSSVELV PAYLLLAEAS LGLGRIVQAE EYLFQAQWTV LKSTDCSNAT HSLLHRNLGL LYIAKKNYEE ARYHLANDIY FASCAFGTED IRTSGGYFHL ANIFYDLKKL DLADTLYTKV SEIWHAYLNN HYQVLSQAHI QQMDLLGKLF ENDTGLDEAQ EAEAIRILTS ILNIRESTSD KAPQKTIFVL KILVMFYYLM MNSSKAQEYG MRALSLAKEQ QLDVHEQSTI QELLSLISTE DHPIT
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Molecular Weight
41.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZMYND12, a member of the zinc finger MYND domain-containing protein family, has emerged as a significant focus of research due to its role in various biological processes, including gene regulation and chromatin remodeling. Studies have shown that ZMYND12 interacts with histone marks, influencing transcriptional regulation and cellular differentiation. Its involvement in the response to DNA damage and cellular stress highlights its potential implications in cancer biology and other diseases. Researchers are particularly interested in the structural and functional characterization of recombinant ZMYND12 protein to understand its mechanistic role in cellular processes. The production of recombinant ZMYND12 allows for detailed studies of its interactions with other proteins and nucleic acids, providing insights into its function within the cell. Additionally, understanding ZMYND12's role in epigenetic regulation could uncover new therapeutic targets for diseases where these processes are disrupted. The investigation of ZMYND12 not only contributes to the broader understanding of gene regulation but also paves the way for potential advancements in targeted therapies for cancer and other pathologies related to dysregulated chromatin dynamics.
